August 2015 in “Evidence Based Women Health Journal (Online)” This study found that inositol was significantly more effective than Metformin in promoting weight reduction, spontaneous ovulation, and pregnancy in patients with polycystic ovary syndrome.
November 2023 in “Animals” This study found that cashmere goats with greater fasted live-weight gain during the non-growing period had increased cashmere yield and staple length, likely due to higher secondary hair follicle activity.
26 citations
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July 2020 in “Fertility and Sterility” Male infertility and genitourinary birth defects are often linked to genetic issues.
6 citations
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April 2021 in “Journal of Mind and Medical Sciences” In this study, most women who experienced both vaginal and Caesarean births preferred and recommended natural delivery, suggesting the need for careful, individualized evaluation of birth conditions.
July 2025 in “Reproductive Biology and Endocrinology” This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.
February 2024 in “Brain research bulletin” This study observed that inhibiting androgenic activity during early postnatal development significantly decreased body weight in female rats by day 90, while affecting food intake and fat distribution in both sexes based on the inhibited testosterone metabolic pathway.
11 citations
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May 2020 in “Sultan Qaboos University medical journal” This study found that while bariatric surgery in Bahrain effectively accelerated weight loss, it was also associated with nutritional deficiencies and gastrointestinal complications.
This study conducted a genome-wide association analysis on 1,125 ewes and identified 24 SNPs associated with wool production traits, and highlighted potential candidate genes like ADAR and TP53 for further research into the genetic mechanisms influencing wool growth in sheep.
77 citations
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March 2004 in “Human Reproduction” This study found that women with symptoms of oligomenorrhoea and/or hirsutism are more likely to have polycystic ovaries and less favorable biochemical and clinical markers compared to asymptomatic women.
52 citations
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April 2008 in “Therapeutics and clinical risk management” This review covers the use of combined oral contraceptives, particularly drospirenone, for managing polycystic ovary syndrome and discusses related metabolic controversies without reporting new clinical results.
5 citations
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October 2017 in “JOGC/Journal of obstetrics and gynaecology Canada” This review discusses the causes and management of hirsutism and suggests improvement can be achieved with a combination of hair removal, suppression of androgen production, and lifestyle changes over 6 to 9 months.
September 2025 in “JAAD reviews.” In this systematic review and meta-analysis, researchers evaluated the link between alopecia areata and adverse pregnancy outcomes, motivated by the condition's association with other autoimmune diseases that increase pregnancy risks. Results are not provided in the abstract.
26 citations
,
December 2020 in “International Journal of Molecular Sciences” This review explores current and emerging treatments for polycystic ovary syndrome, focusing on managing hyperandrogenism and cardiometabolic risk, but reports no new clinical results.
4 citations
,
August 2021 in “Clinical and Experimental Reproductive Medicine” This review highlights key clinical recommendations from the 2018 international guidelines on PCOS management and questions if these guidelines will be widely adopted in practice.
3 citations
,
September 2025 in “Frontiers in Cardiovascular Medicine” This study reports that women with polycystic ovary syndrome, especially those with a hyperandrogenic pattern, are at a higher risk for cardiovascular disease compared to other PCOS patients, likely due to related metabolic comorbidities.
1 citations
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January 2023 in “Deleted Journal” This article discusses the symptoms, pathophysiology, diagnosis, and treatment options for polycystic ovary syndrome, highlighting early diagnosis benefits, but it reports no new findings.
April 2025 in “The American journal of patient health info.” This source highlights that women with PCOS often face hormonal imbalances leading to symptoms like irregular menstrual cycles and increased risks of conditions such as infertility and type 2 diabetes, while lifestyle changes remain crucial for managing PCOS.
August 2024 in “Medicine” This study found that medroxyprogesterone acetate and ethinyl estradiol with drospirenone were the most frequently prescribed medications for PCOS, with some patients experiencing drug changes or discontinuation due to side effects or therapeutic failure.
January 2022 in “Dubai diabetes and endocrinology journal/Dubai diabetes & endocrinology journal” This case report describes a 16-year-old girl with HAIR-AN syndrome requiring a multidisciplinary approach, including lifestyle changes and hormonal treatments, to manage symptoms and prevent systemic effects.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
This article discusses the impact of hyperandrogenism in polycystic ovary syndrome on women's physical and mental health, but it reports no new experimental findings.
951 citations
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December 2013 in “Clinical epidemiology” This article reviews the prevalence, risk factors, and clinical manifestations of polycystic ovary syndrome, highlighting current treatment and management options, but reports no new research findings.
502 citations
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February 2008 in “The Journal of Clinical Endocrinology & Metabolism” This review discusses hirsutism management guidelines, recommending androgen testing only for women with abnormal hirsutism scores and advocating for combined therapy approaches depending on severity and underlying conditions, but it reports no new clinical results.
136 citations
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April 2010 in “British Journal of Dermatology” This review discusses guidelines for acitretin use in dermatology, reporting its efficacy in severe psoriasis and recommendations for combination therapies, without providing new clinical trial results.
36 citations
,
October 2021 in “Frontiers in Endocrinology” This study highlights the importance of understanding the roles of hyperandrogenemia and insulin resistance in the development and progression of PCOS, emphasizing further research to clarify their mutual influence.
29 citations
,
June 2015 in “Kidney International” This study developed a kidney-specific knockout mouse model lacking the Flcn gene, which recapitulates human Birt-Hogg-Dubé kidney tumorigenesis and shows that mTOR pathway inhibition with rapamycin can suppress tumor growth.
26 citations
,
July 2012 in “Journal of family planning and reproductive health care” This review explores treatment approaches for excess male-pattern body hair in women and emphasizes the importance of effective management, but reports no new clinical findings.
9 citations
,
March 2022 in “Journal of the Endocrine Society” This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.
9 citations
,
July 2021 in “Essays in Biochemistry” This review discusses the roles of steroid hormone receptors in lung function related to COVID-19 and outlines ongoing clinical trials of steroid receptor ligands, but reports no new results.