A Rare Case of Adolescent Girl with Beard-PCOS with a Difference: HAIR-AN Syndrome

    January 2022 in “ Dubai diabetes and endocrinology journal/Dubai diabetes & endocrinology journal ”
    Payal S. Kubsad, Vani Hebbal Nagarajappa, Dhanya Mohan
    TLDR A 16-year-old girl with HAIR-AN syndrome was treated with lifestyle changes and medications to manage her condition.
    The document discusses a rare case of a 16-year-old girl diagnosed with HAIR-AN syndrome, a subtype of PCOS marked by hyperandrogenism, insulin resistance, and acanthosis nigricans. She presented with atypical symptoms such as beard growth, irregular menstrual cycles, and hyperpigmentation. Clinical evaluations showed elevated insulin and testosterone levels. Treatment with lifestyle changes, metformin, spironolactone, and oral contraceptives led to symptom improvement and reduced acanthosis. The case emphasizes the need for early diagnosis and a multidisciplinary approach to manage HAIR-AN syndrome effectively.
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