2 citations
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August 2020 in “JCRPE” This case report describes a girl with Denys-Drash syndrome misdiagnosed with hyperandrogenism due to biotin interference in immunoassays, highlighting the need for awareness of laboratory result discrepancies.
2 citations
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March 2020 in “PubMed” This study found no significant difference in serum biotin levels between patients with telogen effluvium and control subjects.
2 citations
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January 2019 in “Elsevier eBooks” This review discusses biotin's role in nutrition and suggests no benefit to supplementing it for hair, nails, and skin in healthy individuals; it reports preliminary findings that high dosages may help some multiple sclerosis patients.
2 citations
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December 2014 This review discusses the role of biotin in metabolism and the consequences of its deficiency, reporting no new clinical results.
2 citations
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January 1997 in “Journal of Clinical Biochemistry and Nutrition” This study found that germ-free mice on a biotin-deficient diet exhibited significant weight loss and severe alopecia, unlike conventional mice on the same diet.
1 citations
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July 2023 in “Plastic and Aesthetic Nursing” Biotin and collagen may improve hair health.
1 citations
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July 2022 in “Dermatologic Therapy” This study found that a 6-week treatment with both brands of biotin and dexpanthenol significantly improved hair fall count and hair density in people with diffuse pattern hair loss, with no significant difference between the two brands.
1 citations
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February 2022 in “Biological Trace Element Research” In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.
1 citations
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February 2022 in “Journal of the American Academy of Dermatology” This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.
1 citations
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February 2020 in “PubMed” This study found that a topical compounded formulation may improve hair density and general appearance in male patients with androgenetic alopecia after 6 months of use.
1 citations
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October 2018 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” In this study, the researchers reported that women with diffuse telogen alopecia who took Wolvit® (biotin 5 mg) daily for 3 months showed a significant decrease in hair in the telogen phase and an increase in hair thickness and growth speed.
1 citations
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January 2018 in “Journal of cosmetology & trichology” This study found that a new hair loss lotion containing various cosmetic ingredients significantly increased total hair fibers and anagen hairs in individuals with androgenetic alopecia and telogen effluvium, while also improving visual hair characteristics and receiving positive user feedback without adverse effects.
1 citations
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December 2017 in “Skin appendage disorders” Biotin may help women with hair loss who have low biotin levels, but more research is needed.
1 citations
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July 2012 in “EFSA Journal” The Panel concluded that there is no established cause and effect relationship between the specified vitamin and pumpkin seed oil combination and the maintenance of normal hair in healthy adults.
1 citations
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January 1999 in “Proceedings of the British Society of Animal Science” This research investigates apoptosis and bcl 2 expression in hair follicles cultured with and without biotin, but it reports no new results.
1 citations
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January 1997 in “Proceedings of the British Society of Animal Science” This review addresses the role of biotin in animal metabolism, emphasizing the need for further research to understand its dietary and microbial sources in different developmental stages in pre-ruminant and mature ruminant animals, without reporting new experimental results.
August 2026 in “Bulletin of the Medical Institute of Continuing Education” This observational study found that a high-dose biotin regimen of 10,000 mcg/day reduced hair loss and improved hair and scalp conditions in female patients with androgenic alopecia, with effects lasting beyond treatment discontinuation, warranting further investigation into biotin's role in combination therapy.
July 2026 in “Pakistan BioMedical Journal” This study observed that social media significantly influences biotin supplement use among young women in Pakistan, often outweighing professional medical advice.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
This systematic review found no consistent evidence supporting the effectiveness of biotin supplementation for alopecia treatment unless there is a documented deficiency.
In this study, GV-350 treatment over three months improved iron status and reduced the impact of Telogen Effluvium on quality of life among 20 iron-deficient women, with no adverse events reported.
September 2025 in “Journal of Pakistan Association of Dermatologists” This randomized controlled trial reported that combining oral Biotin supplements with PRP offered no additional benefits for hair regrowth in patients with Androgenetic Alopecia compared to PRP alone.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
June 2025 in “Current Issues in Molecular Biology” In this study, researchers using a UVB-induced mouse model identified the gene COL7A1 as a novel marker for hair luster, finding that minoxidil, caffeine, and biotin effectively restored its expression, indicating potential therapeutic strategies.
This review examines clinical studies on the effectiveness of biotin in treating hair loss, detailing its role in hair health, recommended usage guidelines, and potential side effects, aiding physicians and patients interested in hair loss prevention and treatment.
May 2025 in “Health Science Reports” This study reported that applying Serum WS Biotin, a water-soluble form of D-Biotin, daily for 3 months significantly reduced hair shedding and increased hair strength in volunteers with moderate to excessive hair shedding, while showing good skin compatibility.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” This study identified that biotin ingestion led to interference in immunoassay results, falsely indicating high testosterone and insulin levels in a 28-year-old female patient, thus complicating her clinical assessment and treatment planning until recognized and resolved.
September 2024 in “Cosmoderma” This study highlights that the popular marketing of biotin for hair loss treatment in healthy individuals lacks scientific support, as evidenced by a review of relevant clinical trials.
September 2024 in “Meditsinskiy sovet = Medical Council” This source reports that biotin, a water-soluble vitamin B7, may benefit skin, hair, and nail health, including various types of alopecia, without the risk of hypervitaminosis even at high doses.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.