Restoration of Hair Luster via Novel Biomarker COL7A1 by Minoxidil, Caffeine, and Biotin

    Ngoc Ha Nguyen, Young In Lee, Hughes Do … Ju Hee Lee
    Studysummary In this study, researchers using a UVB-induced mouse model identified the gene COL7A1 as a novel marker for hair luster, finding that minoxidil, caffeine, and biotin effectively restored its expression, indicating potential therapeutic strategies.
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    Research cited in this study 22

    1. Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology Molecules · 2025
    2. Efficacy and Safety of Latilactobacillus Curvatus LB-P9 on Hair Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Frontiers in Nutrition · 2024
    3. Atomistic Characterization of Healthy and Damaged Hair Surfaces: A Molecular Dynamics Study of Fatty Acids on Protein Layer ChemBioChem · 2024
    4. Efficacy and Safety of Skin Radiance Collagen on Skin and Hair Matrix: A Placebo-Controlled Clinical Trial in Healthy Human Subjects Clinical, cosmetic and investigational dermatology · 2024
    5. Quantitative Analysis of Hair Luster in a Novel Ultraviolet-Irradiated Mouse Model International journal of molecular sciences · 2024
    6. Age-Related Changes in Scalp Biophysical Parameters: A Comparative Analysis of the 20s and 50s Age Groups Skin Research and Technology · 2023
    7. Protection and Restoration of Damaged Hair via a Polyphenol Complex by Promoting Mechanical Strength, Antistatic, and Ultraviolet Protection Properties Biomimetics · 2023
    8. A Novel Hair Restoration Technology Counteracts Androgenic Hair Loss and Promotes Hair Growth in a Blinded Clinical Trial Journal of Clinical Medicine · 2023
    9. Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer Cells · 2020
    10. Pathogenesis and Clinical Features of Alopecia in Epidermolysis Bullosa: A Systematic Review Pediatric Dermatology · 2019
    11. Mechanism of Cuticle Hole Development in Human Hair Due to UV Radiation Exposure Cosmetics · 2018
    12. Mechanism of Action of Minoxidil in the Treatment of Androgenetic Alopecia Is Likely Mediated by Mitochondrial Adenosine Triphosphate Synthase-Induced Stem Cell Differentiation PubMed · 2018
    13. A Review of the Use of Biotin for Hair Loss Skin appendage disorders · 2017
    14. Twelve-Point Scale Grading System of Scanning Electron Microscopic Examination to Investigate Subtle Changes in Damaged Hair Surface Skin research and technology · 2016
    15. A New Strategy to Modulate Alopecia Using a Combination of Two Specific and Unique Ingredients PubMed · 2013
    16. Characterization of the Human Hair Keratin-Associated Protein 2 (KRTAP2) Gene Family Journal of Investigative Dermatology · 2012
    17. A Nutritional Supplement Formulated with Peptides, Lipids, Collagen, and Hyaluronic Acid Optimizes Key Aspects of Physical Appearance in Nails, Hair, and Skin Journal of nutrition & food sciences · 2012
    18. Photoaggravation of Hair Aging International Journal of Trichology · 2009
    19. Molecular Evolution of the Keratin Associated Protein Gene Family in Mammals: Role in the Evolution of Mammalian Hair BMC Evolutionary Biology · 2008
    20. Human Hair Keratin-Associated Proteins ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    21. Expression of Novel Keratin-Associated Protein 5 Genes in the Cuticle Layer of Human Hair Follicles Journal of dermatological science · 2005
    22. Immunofluorescence Analysis of the Basement Membrane Zone Components in Human Anagen Hair Follicles Experimental Dermatology · 2003

    Related research 7

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