The Detection of Apoptosis and Bcl-2 in Isolated Secondary Mohair Follicles (Growing and Quiescent), Cultured In Vitro in the Presence or Absence of Biotin

    January 1999 in “ Proceedings of the British Society of Animal Science ”
    A.M. Tahmasbi, H. Galbraith, J. R. Scaife, D. Finn
    TLDR Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
    The study investigated apoptosis and bcl2 expression in secondary mohair follicles cultured in vitro with or without biotin supplementation. Apoptosis, a programmed cell death process, was linked to reduced hair growth and follicle viability, potentially due to decreased bcl2 expression. Previous research indicated that biotin deficiency negatively affected follicle viability and DNA synthesis. This study aimed to explore how biotin presence or absence influenced apoptosis and bcl2 in growing or quiescent follicles.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 39 results

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  643 upvotes 9 months ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

      community Sandalore: a scientific homemade approch

       19 upvotes 7 years ago
      The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

      community Chat is this real? Compound called clascoterone

      in Research/Science  583 upvotes 2 weeks ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  64 upvotes 5 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

      in Product  15 upvotes 6 months ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

    Similar Research

    5 / 1000+ results