The Detection of Apoptosis and Bcl-2 in Isolated Secondary Mohair Follicles (Growing and Quiescent), Cultured In Vitro in the Presence or Absence of Biotin
January 1999
in “
Proceedings of the British Society of Animal Science
”
TLDR Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
The study investigated apoptosis and bcl2 expression in secondary mohair follicles cultured in vitro with or without biotin supplementation. Apoptosis, a programmed cell death process, was linked to reduced hair growth and follicle viability, potentially due to decreased bcl2 expression. Previous research indicated that biotin deficiency negatively affected follicle viability and DNA synthesis. This study aimed to explore how biotin presence or absence influenced apoptosis and bcl2 in growing or quiescent follicles.
