Effect of Primary Biotin Deficiency on the Skin of Germ-Free and Conventional Mice Fed a Purified Biotin-Deficient Diet Without Supplementation with Egg White
January 1997
in “
Journal of Clinical Biochemistry and Nutrition
”
Studysummary This study found that germ-free mice on a biotin-deficient diet exhibited significant weight loss and severe alopecia, unlike conventional mice on the same diet.
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