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This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.

This review examines glycopeptide hydrogels as biomimetic materials for tissue regeneration and other biomedical applications, describing their design, properties, and potential uses, and highlighting future advancements in replicating natural tissue environments for precision medicine.

This study found that mouse astrocytes formed cell spheres on agarose surfaces, acquired stem cell-like features, and their derived stem cells effectively differentiated into neurons that helped regenerate damaged nerves.

This review highlights the development and assessment of human-relevant models for cutaneous wound healing, emphasizing that a combination of systems, such as organoid platforms and skin-on-a-chip systems, is necessary to overcome limitations of traditional methodologies and address chronic wound challenges.

This mini-review reports that advances in microbioreactor technology, particularly with microfluidics, significantly enhance eukaryotic cell-based biomedicine by improving productivity, scalability, and reproducibility in applications like CAR T-cell manufacturing and organoid growth, though challenges in scalability and material selection remain.

This study reports that Echinacea-loaded silk fibroin/chitosan dressings may effectively promote scarless skin regeneration and accelerate wound healing compared to conventional treatments.

This review highlights that Microneedle Hydrogels may offer promising advantages for diabetic foot ulcer treatment due to their minimally invasive application and effective drug delivery capabilities.

This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.

This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.

In this study, researchers demonstrated that fibroblasts derived from human embryonic stem cells can be used to create tissue-engineered dermal substitutes, effectively repairing mouse skin wounds within 20 days, highlighting a promising method for clinical applications in skin repair.

This review discusses the current evidence on platelet-rich plasma therapy's biological mechanisms and clinical applications, highlighting its promise in regenerative medicine and the challenges to its integration in nursing practice.

This review discusses the development of liposome-based delivery systems to enhance skin wound healing, highlighting their advantages and potential applications, but reports no new clinical results.

This study reports that despite advancements in tissue engineering and biomaterials, translating laboratory findings into effective clinical treatments for urethral reconstruction remains inadequate due to lack of standardization and short clinical trial follow-ups.

In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.

In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.

This research explores the potential of Gel-SHP hydrogels in tissue regeneration, suggesting they could contribute to new methodologies and understanding in wound healing and dermal shell formation, but results are not detailed.

In this mouse study, the researchers found that cryopreserving nanofat at -20°C maintained its viability and regenerative potential, comparable to freshly generated nanofat, supporting its potential for repeated use in regenerative applications.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

This review discusses the development and impact of barbed sutures on surgical outcomes across various procedures but reports no new clinical results.

This review discusses stem cell therapy as a promising treatment for epidermolysis bullosa, highlighting preliminary successes in treating skin lesions but noting the need for further research on effectiveness and safety.

This review outlines current European legislation and manufacturing standards for platelet-rich plasma (PRP) products and provides guidance for clinicians implementing autologous PRP treatments, without reporting new clinical results.

This study reviewed the efficacy of mechanical fractionation techniques to produce tissue stromal vascular fraction (tSVF) and found that tSVF injections are particularly effective for conditions like osteoarthritis and wound healing, with centrifugation before fractionation improving isolation efficiency regardless of preparation method.

In this retrospective study at Lausanne University Hospital, 61% of 48 patients with tendinopathies reported favorable outcomes after a single standardized autologous PRP injection, while 36% needed two, and effectiveness was unrelated to platelet concentration, activity level, age, or gender.

This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

In this study, conditioned medium from genetically engineered mesenchymal stem cells significantly improved wound healing, re-epithelialization, hair follicle formation, and angiogenesis in diabetic mice, suggesting a promising new approach for diabetic ulcer care.

This review discusses pre-clinical research on ultrasound-mediated sonoporation for tissue regeneration and reports no clinical results; the authors suggest the method is safe and highlight challenges to clinical translation.

This study found that platelet-rich fibrin lysates modulate chemokine expression, reducing inflammation in oral squamous carcinoma cells, but increasing expression in primary oral epithelial cells.

This article reviews the evolving understanding of hematopoietic stem cells, including their heterogeneity and the role of cytokines in lineage determination, and reports no new results.

In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.