Subcutaneous Injection of Genetically Engineered Exosomes for Androgenic Alopecia Treatment
May 2025
in “
Frontiers in Bioengineering and Biotechnology
”
genetically engineered exosomes EX104 VEGFA WNT10B FGF7 androgenic alopecia C57BL/6 mouse models dermal papilla cell proliferation dihydrotestosterone hair follicle microenvironment blood vessel formation hair follicle proliferation hair coverage follicular miniaturization androgen receptor mRNA expression AGA DHT
Studysummary In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.
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