October 2025 in “INSOLOGI Jurnal Sains dan Teknologi” In this laboratory study on rabbits, the researchers observed that both FET and FHE fractions improved hair length and weight, but minoxidil still led to better results, highlighting the comparative effects of different treatments on hair growth over 28 days.
July 2025 in “International Journal of Allied Medical Sciences and Clinical Research” This review compiles current knowledge of Eclipta prostrata's botanical details, ethnomedical uses, phytochemical components, and various pharmacological activities, emphasizing its potential for modern pharmaceutical formulations based on its anti-inflammatory, antioxidant, anticancer, and other therapeutic properties.
February 2026 in “ACS Applied Materials & Interfaces” This study developed a novel treatment method using carbon dots from Cinnamomum burmannii leaves, which improved hair regeneration and thickness in an AGA mouse model by promoting cell proliferation, angiogenesis, and reducing inflammation through multiple signaling pathways.
This pilot study found that a novel nanoemulsion with Bakuchiol and Neem oil significantly improved hair regrowth in adults with Alopecia Areata without serious side effects, providing a promising natural alternative.
September 2025 in “International Journal for Research in Applied Science and Engineering Technology” This paper discusses the potential benefits of incorporating guava leaf extracts into skincare, hair care, and oral care products, highlighting their antibacterial, antioxidant, and acne-treating properties, as well as their possible effects on dandruff removal and hair loss reduction.
December 2025 in “International Journal of Molecular Sciences” In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.
July 2026 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This study found that serum containing keratin extract from chicken feathers combined with Aloe vera showed promising effectiveness for anti-hair loss treatment, with certain combinations outperforming the positive control in measures of hair strength and growth in rabbits.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
March 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.
February 2025 in “Natural Product Communications” This study found that combining natural extracts significantly boosted the stem cell functions of dermal papilla cells by enhancing β-catenin stability, promoting hair growth potential in vitro.
June 2024 in “Deleted Journal” This review explored the potential of medicinal plants and natural compounds as alternative treatments for baldness, identifying several with anti-inflammatory and antioxidant properties that may help reduce hair loss.
April 2026 in “International Journal for Research in Applied Science and Engineering Technology” In this study, the developed polyherbal shampoo with Hibiscus rosa-sinensis exhibited good stability and cleansing properties, suggesting it may be an effective natural alternative to synthetic anti-hair fall products.
6 citations
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May 2022 in “Journal of Cosmetic Dermatology” In this study, Lagerstroemia indica extract was found to significantly promote hair growth and prevent hair loss in human trials, likely through the regulation of specific signaling pathways, indicating its potential as a cosmetic treatment for hair loss prevention.
December 2021 in “Prosiding Seminar Nasional Kesehatan” In this study, the hair tonic made from the ethanol extract of bandotan leaves, applied on local male rabbits for 21 days, demonstrated significant hair growth activity, especially at a 20% concentration, showing the highest hair length and weight improvements.
October 2024 in “Jurnal Pharmascience” This study concluded that formulations of celery and candlenut extracts meet the necessary criteria for use as a spray preparation aimed at promoting hair growth, based on evaluations of physical properties and consistency.
February 2026 in “Journal of Sylva Indonesiana” This study found that the heartwood extract of Avicennia marina demonstrated strong antioxidant activity, with an IC50 value of 61.50 µg/mL, suggesting potential for development into supplements or topical applications targeting degenerative diseases related to oxidative stress.
January 2009 in “한방재활의학과학회지” In this study, Saengbal-eum-2 (Shengfa-yin-2) promoted hair regrowth and decreased specific inflammatory cytokines in a mouse model compared to a control.
7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
January 2022 in “JURNAL BIOSAINS” This study found that a hair tonic made with 10% cassava leaf extract in combination with rose water juice improved hair length growth in rabbits compared to a commercial product.
6 citations
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January 2009 This study found that topical application of Russelia equisetiformis methanol extract significantly increased hair growth in albino Wistar rats, potentially due to its triterpene and flavonoid content.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, Platycladus orientalis leaf extract loaded into hyaluronic acid microneedles was found to promote hair follicle growth by enhancing the environment for hair cell proliferation and activating repair pathways, suggesting potential as a treatment for androgenic alopecia.
This source reports the versatile use of Bhringraj (Eclipta Alba) for liver health, hair care, and digestive regulation, noting its potential benefits in conditions like alopecia areata due to its liver-protective and hair-strengthening properties.
October 2022 in “Asian journal of healthy and science” This study found that a 20% concentration of mother-in-law's tongue leaf extract promoted hair growth in male rabbits, with effectiveness comparable to a positive control.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
June 2022 in “Journal of Cosmetic Dermatology” This study found that the ethanolic extract of Acanthus ebracteatus demonstrated potential as an anti-hair loss treatment by promoting dermal papilla cell proliferation, inhibiting 5α-reductase activity, and reducing inflammation in vitro.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, PA-011 extract was reported to promote hair growth and alleviate alopecia areata symptoms in mice by reducing skin inflammation and modulating skin microbiota.
April 2011 in “The FASEB Journal” In this study, aralia continentalis extract was observed to promote hair follicle development in mice through anagen progression, with the low dose being more effective than the high dose.
March 2025 in “Research Square (Research Square)” This study explored the potential of the lysate and lipoteichoic acid from Lactiplantibacillus plantarum APsulloc 331261 to improve scalp seborrheic dermatitis by modulating inflammatory and lipogenesis pathways in vitro, suggesting potential as a natural treatment option.
January 1988 in “Skin research”
In this laboratory study, the methanolic extract of Eclipta alba demonstrated significant anthelmintic activity against earthworms (Pheretima posthuma), causing paralysis and death at doses of 50-100 mg/ml, with stronger effects observed at higher concentrations compared to the standard treatment, albendazole.