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This review examined evidence on non-systemic treatments for acne vulgaris and related skin complications, finding very low-certainty evidence that benzoyl peroxide may reduce lesion counts but may also increase the risk of minor adverse events, highlighting the need for higher-quality research for effective therapies.

This study found that carvone, a plant-derived compound, decreases melanin content and inhibits melanoma cell proliferation through the cAMP pathway, suggesting potential benefits for treating melanomas and other hyperpigmentation disorders.

This study found that the 11R-No. 10 peptide, delivered transdermally, significantly inhibited melanogenesis and produced a whitening effect in a UV-induced sun-tanning guinea pig model without cytotoxicity.

This study found that flavonoids with two hydroxyl groups in their B-ring, such as sterubin and luteolin, supported the regeneration of pigmented hair after skin injury, unlike those with one hydroxyl group.

This study demonstrated that benzothiazepines, such as diltiazem and JTV-519, exert anxiolytic-like effects through allopregnanolone biosynthesis in mice, similar to carbamazepine.

This study reports a new industrial process for making finasteride using novel protective groups, demonstrated through spectral data of newly prepared compounds.

This study found that Melamax®, originally developed as an eco-friendly hair dye, provides significant protection against ultraviolet-induced oxidative and inflammatory damage in keratinocytes by modulating gene expression and signaling pathways, highlighting its dual potential for cosmetic coloration and skin photoprotection.

This synthesis report details the successful development of a C-14 labeled isotopomer of LY300502, a 5α-reductase inhibitor, through a multi-step radiochemical process.

This study reports that a carbopol gel formulation with melatonin shows potential for extended drug release and biocompatibility in dermal applications due to its favorable bio-pharmaceutical properties.

Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.

This study found that the presence of benzeneseleninic acid in commercial anhydride samples lowered the reaction rate during the oxidation of a finasteride intermediate compared to pure anhydride.

This study found that BEO inhibited cell proliferation and inflammatory mediator release in a human keratinocyte acne model and reduced acne lesion severity in a rabbit model, suggesting its potential as a natural alternative to conventional acne treatments.

In this study, synchrotron-powered infrared microscopy revealed that hair follicles are a favored penetration pathway for cyanophenol and ethylhexyl methoxycinnamate in human skin, without altering protein secondary structure.

This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.

In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.

A man developed an allergic skin reaction after using brimonidine for rosacea.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.

This study investigated the use of methylene blue in a niosomal hydrogel for photodynamic treatment of acne and found that it led to significant improvement in inflammation compared to IPL treatment.

This narrative review discusses the promising role of photobiomodulation in dermatology, emphasizing its non-invasive nature and potential benefits, but acknowledges the need for further research to establish standard protocols.

This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.

This study reports that A132, a hair dye ingredient, induces phototoxicity and photogenotoxicity via mitochondrial apoptosis when exposed to sunlight, suggesting potential risks of oxidative stress and hair damage.

This study found that benzodiazepine therapy in women with idiopathic hirsutism significantly increased sex hormone binding globulin and decreased dehydroepiandrosterone sulphate, but did not significantly affect hair growth.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

This study presents three spectrophotometric methods for determining finasteride in bulk and tablet forms, showing a linear relationship between absorbance and finasteride concentration.

This study found that silencing clock genes BMAL1 or PER1 in human hair follicles increased melanin content and melanocyte activity, suggesting these genes influence pigmentation.

This study demonstrates that Bazi Bushen capsules may have therapeutic potential against skin photoaging in mice by enhancing NRF2 expression and targeting the KEAP1-NRF2 pathway.

This study introduces a new intracavity frequency modulation technique for tunable picosecond optical parametric oscillators, enhancing chemical contrast in coherent Raman imaging by allowing real-time subtraction of background signals.