Search

everythinglearnresearchcommunity

for

Search:↓

The human skin's outer layer has more variety in cell types and development paths than previously thought.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

DNMT3A is crucial for healthy skin and hair growth.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

CD4+ skin cells may be precursors to basal cell carcinoma.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Understanding skin structure and development helps diagnose and treat skin disorders.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Different types of skin stem cells can change and adapt, which is important for developing new treatments.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.