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Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Human dermal stem cells can become functional skin pigment cells.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Epidermal stem cells maintain skin health through specific niches and signaling pathways.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

The engineered skin substitute helped grow skin with hair on mice.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Activating Notch signaling can kill basal cell carcinoma cells.

The method increases stem-like cells for better skin regeneration.

A specific group of skin stem cells was found to help maintain hair follicle cells.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.