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This study suggests that targeting the activation of transit-amplifying cell-derived progenitor cells may help prevent hair loss from chemotherapy and radiotherapy by promoting hair follicle regeneration.

This study suggests that using sebaceous glands from rat tail skin samples may effectively capture hair follicle stem cells, potentially aiding skin regenerative medicine when available tissue is limited.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This study reported that ELL is crucial for maintaining the proliferative capacity of the basal layer in human epidermal keratinocytes by stabilizing RNA polymerase II at the transcription start site.

This study found that poly(adenosine diphosphate-ribose) synthesis in human skin varies by cell type and condition, with distinct patterns in psoriatic, cancerous, and normal tissues.

TEDAR is crucial for skin cell differentiation and barrier formation.

This study found that basal cell carcinoma exhibits patterns of hair follicle differentiation but is stuck in telogen arrest, which can be rescued by adding noggin and TGF-β2 in vitro.

This research studied the effect of local testosterone propionate applications on rabbit epidermal mitotic activity but reports no new results.

This case report describes a non-thymoma-associated exfoliative dermatitis in an 8-year-old cat, where treatment with cyclosporine A alongside prednisolone and antibiotics resolved skin lesions without relapse after an initial recurrence.

This study found that basal lower proximal cup cells in mice are key to regenerating hair follicles after chemotherapy-induced damage, while traditional bulge stem cells remain inactive.

This study found that epidermal Wnt production is crucial for forming the skin's spinous layer through a BMP-FGF signaling cascade, although Wnt from basal cells is not needed for their differentiation.

This review highlights that the epidermis acts as an endocrine organ, synthesizing and responding to hormones such as corticosteroids and Vitamin D, impacting processes like hair growth and immune response, and participating in regulating endocrine balance.

This study investigated the role of the ABCA4 gene in human keratinocytes and hair follicle stem cells and found that silencing the ABCA4 gene increases the harmful effects of all-trans-retinal on hair follicle stem cells.

In this study, the researchers observed that antiandrogen treatment with Cyproterone acetate led to atrophy of pilo-sebaceous units and may activate Langerhans cells, contributing to local inflammation.

In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.

This study found that ruby laser hair removal causes microscopic epidermal damage but does not lead to cellular hyperproliferation, unlike ultraviolet-irradiated cell damage.

The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.

This research explored the components of stem cell niches to better understand how epidermal stem cells are maintained, focusing on CD271+ cells in specific skin layers.

This study found that "early" transit amplifying cells, marked by CD271, are the first keratinocyte stem cell progenitors with distinct features, playing a significant role in early epidermal differentiation and regeneration.

This review highlights the critical role of TGF-β and FGF signaling pathways in the development and regeneration of skin layers, particularly the dermis, and discusses their significance in advancing future clinical applications in dermatology.

In this study, researchers observed distinct aging signatures in mouse keratinocytes, with increased expression in older mice, and noted relevant pathway changes that were also evident in human skin, suggesting potential insights into intrinsic skin aging.

In this study, researchers reported that CD34 expression in the isthmic region of canine hair follicles suggests a potential stem cell compartment in this area.

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

This study found that hair germ and epidermal basal cells differ in keratin expressions in rat hair tissues, with hair-specific keratins appearing after the differentiation of each layer.

This research reexamined transcriptomic data to study stem and progenitor cell proliferation in psoriasis, finding that the number of committed progenitor cells increased eight-fold in psoriatic skin without altering stem cell numbers, potentially identifying new therapeutic targets.

This review summarizes late-breaking abstracts from the American Society for Laser Medicine and Surgery, 2018, and reports no new clinical findings.

This study reports that tissue-engineered skin using ES cell-derived epidermal stem cells and collagen sponge successfully healed full thickness skin defects in mice, forming epidermis and structures resembling glands and hair follicles.

This review discusses the biological features and clinical applications of epidermal stem cells in wound healing and tissue regeneration, emphasizing the need for further understanding of their mechanisms.

This study found that the RNA helicase DDX6 is essential for maintaining self-renewal in epidermal progenitor cells by promoting the translation of proliferation regulators and degrading differentiation-inducing mRNAs.

This study found that differentiated cells of the corneal epithelium can be converted to hair and interfollicular epidermis through a multistep process involving dermal developmental signals.