The Expression of Equine Keratins K42 and K124 Is Restricted to the Hoof Epidermal Lamellae of Equus Caballus

    September 2019 in “ PLoS ONE ”
    Caitlin Armstrong, Lynne Cassimeris, Claire da Silva Santos … Hannah Galantino‐Homer
    Studysummary This study demonstrated that keratin K124 is specific to equine hoof lamellar tissue and established monoclonal antibodies that can specifically recognize K124 without cross-reacting with other tissues.
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    Research cited in this study 9

    1. Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals Molecular Biology and Evolution · 2018
    2. A Curated Catalog of Canine and Equine Keratin Genes PLoS ONE · 2017
    3. Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity International review of cell and molecular biology · 2014
    4. Comparative Anatomy of Mouse and Human Nail Units The Anatomical Record · 2013
    5. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    6. The Organization of the Keratin I and II Gene Clusters in Placental Mammals and Marsupials Show a Striking Similarity European Journal of Cell Biology · 2005
    7. A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n, Exhibits Preferred Expression in Nail Tissue Journal of Investigative Dermatology · 2004
    8. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and Its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000
    9. Keratin Expression in the Normal Nail Unit: Markers of Regional Differentiation British Journal of Dermatology · 2000