research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
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research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Male Androgenetic Alopecia
Hair loss in men treated best with early medication or transplant, new treatments researched.
research Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update
Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
research Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men
Best hair growth results from combining finasteride and minoxidil.
research Melatonin Increases Anagen Hair Rate in Women With Androgenetic Alopecia or Diffuse Alopecia: Results of a Pilot Randomized Controlled Trial
Melatonin helps hair growth in women with hair loss.
research Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse
Human hair follicles can regenerate after removal, but with low success rate.
research The Effects of Minoxidil, 1% Pyrithione Zinc, and a Combination of Both on Hair Density: A Randomized Controlled Trial
Minoxidil and pyrithione zinc combo most effectively increases hair density.
research Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences
Multiple treatments work best for hair loss.
research Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia
The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
research Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss
Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.
research Hair Restoration Surgery: The State of the Art
Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Ketoconazole as an Adjunct to Finasteride in the Treatment of Androgenetic Alopecia in Men
Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research Microbiome in the Hair Follicle of Androgenetic Alopecia Patients
Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.
research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia
PRFM may help treat hair loss, especially in mild cases.
research Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades
Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.
research Hair Loss And Regeneration Performed On Animal Models
Animal models are crucial for learning about hair loss and finding treatments.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
research Pharmacologic Management of Pattern Hair Loss
Treat pattern hair loss with finasteride and topical minoxidil.
research Topical Minoxidil in Androgenetic Alopecia: Scandinavian and Middle East Experience
The study found that using 2% minoxidil solution can help grow hair and is safe.
research Laser Hair Transplantation
Laser hair transplantation can be effective but should be limited to small areas and requires more training to ensure safety and effectiveness.
research TRPS1 Mutation Associated with Trichorhinophalangeal Syndrome Type 1 with 15 Supernumerary Teeth, Hypoplastic Mandibular Condyles with Slender Condylar Necks and Unique Hair Morphology
A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.
research Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle
Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
research Bioactives in Chinese Proprietary Medicine Modulate 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Environment of the Anagen Follicle
The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.