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The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

The session covered updates on skin treatments, including radiotherapy, imiquimod, acitretin, JAK inhibitors, and strategies for managing rosacea and preventing surgical infections.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.

FOXN1 gene variants cause low T cells and immune issues from birth.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Skin aging reflects overall body aging and can indicate internal health conditions.

Lupus treatment requires a combination of drugs and therapies, with research needed for new options.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

NK cells play a role in skin diseases like eczema and psoriasis.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.