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GlossaryBcl-2 family

regulates cell death and survival through protein interactions

The Bcl-2 family, also known as the B-cell lymphoma 2 family, is a group of proteins that play a crucial role in regulating cell death (apoptosis). These proteins can either promote survival or trigger cell death, and their balance is essential for maintaining healthy tissue function and preventing diseases like cancer.

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research Alex De La Iglesia: We Are All Perverse

January 2000 in “Cambio 16”

Bcl-2 affects hair growth and pigmentation by controlling cell death.

research Protein Kinase Akt2/PKBβ Is Involved in Blastomere Proliferation of Preimplantation Mouse Embryos

7 citations , September 2019 in “Journal of Cellular Physiology”

Akt2 protein is essential for normal cell division in early mouse embryos.

research Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth

7 citations , January 2019 in “Annals of dermatology/Annals of Dermatology”

Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.

Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

47 citations , April 2000 in “The American journal of pathology”

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

research A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

17 citations , January 2019 in “Journal of cancer”

The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.

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community The end of balding: We may have just found the secret to hair regrowth

in Technology 680 upvotes 11 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.

community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

in Research/Science 4 upvotes 3 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

in Update 14 upvotes 4 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.