Montagna Symposium 2017—Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment

    May 2018 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Jakub Tolar, Johann Bauer, Daniel H. Kaplan, Sancy A. Leachman, John A. McGrath, Amy S. Paller, Kelly Griffith-Bauer, Clara E. Stemwedel, Molly Kulesz‐Martin
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    TLDR The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.
    The 66th Annual Montagna Symposium in 2017 focused on precision dermatology, integrating molecular disease understanding with clinical applications of big data. Key discussions included gene discovery, predictive phenotyping, and molecular dissection of cancers like melanoma, with advances in single-cell RNA sequencing and CRISPR-Cas9 gene editing highlighted for treating genetic disorders. Novel immunotherapies, regenerative medicine approaches, and the role of ceramides in overcoming drug resistance were also discussed. The symposium emphasized the importance of understanding disease mechanisms for targeted therapies, with successful examples in psoriasis, atopic dermatitis, and promising treatments for alopecia areata through JAK/STAT pathway inhibition. The event underscored the need for collaborative efforts and validation of new technologies in advancing dermatologic care.
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