Drugs Targeting the JAK/STAT Pathway for the Treatment of Immune-Mediated Inflammatory Skin Diseases: Protocol for a Scoping Review

    May 2019 in “ BMJ Open
    Francisco J. García, Pedro Jesús Gómez‐Arias, Jorge A. Hernández, Ana Montilla, Jesús Gay-Mimbrera, Macarena Aguilar-Luque, Isabel Viguera-Guerra, Antonio Vélez García‐Nieto, Beatriz Isla-Tejera, Juan Ruano
    The document outlined a protocol for a scoping review to evaluate the evidence on drugs targeting the JAK/STAT pathway for treating dermatological diseases such as psoriasis, atopic dermatitis, alopecia areata, vitiligo, and melanoma. Despite the growing evidence of JAK/STAT inhibitors' potential in dermatology, none had been approved for skin disease treatment at the time. The review aimed to systematically gather and analyze existing studies using a five-stage methodology from the Joanna Briggs Institute, with results to be reported following the PRISMA-ScR guidelines. The findings were intended for dissemination through peer-reviewed publications and conference presentations.
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