7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
71 citations,
September 2006 in “Cell Transplantation” Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
2 citations,
March 2021 in “Journal of Cosmetic Dermatology” Umbilical cord-derived media is safe and effective for hair growth.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
165 citations,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
160 citations,
January 2017 in “Development” Blood vessels and specific genes help turn cartilage into bone when bones heal.
154 citations,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
13 citations,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
3 citations,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
181 citations,
February 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
33 citations,
December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
16 citations,
October 2014 in “Cell death and disease” FoxN1 overexpression in young mice harms immune cell and skin development.
2 citations,
January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
17 citations,
March 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
2 citations,
March 2014 in “Turkderm” Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
1 citations,
October 2022 in “Molecular therapy” The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
54 citations,
January 2009 in “British Journal of Dermatology” Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
26 citations,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
5 citations,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
55 citations,
April 2015 in “BMC medicine” Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
1 citations,
February 2020 in “Regenerative Medicine” Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.