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Male pattern baldness involves genetics, hormones, and needs better treatments.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Tiny needles with valproic acid can effectively regrow hair.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Using fat-derived stem cells for hair loss treatment is safe and effective, improving hair growth and patient satisfaction.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.