November 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that 4-aminopyridine, a potassium channel blocker, greatly improves skin wound healing by accelerating wound closure, enhancing tissue regeneration, and promoting hair follicle neogenesis.
1 citations
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July 1999 in “Plastic and Reconstructive Surgery” The article discusses how to fix bad results from hair restoration surgery, with different doctors suggesting methods like adding more grafts, moving transplanted hair, or using smaller grafts.
6 citations
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July 2021 in “Microbial biotechnology” This study found that combining LED yellow light with an engineered strain expressing CXCL12 improved wound healing and reduced inflammation in a mouse model of scald wounds.
4 citations
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January 2009 in “Indian Journal of Plastic Surgery” This study observed that good surgical outcomes for secondary cicatricial alopecia were achieved in 18 patients, with method selection influenced by the size, location, and shape of alopecia.
January 2025 in “Medicina” This study reviews emerging techniques in acute burn wound therapy, noting innovations such as advanced imaging for better wound assessment and new closure strategies aimed at improving healing, graft survival, and scarring outcomes, while emphasizing the need for further research to validate these methods.
April 2005 in “Clinics in Plastic Surgery” This review discusses the use of lasers in plastic surgery for various conditions and reports no new clinical results; the authors note effective treatment options for patients across different ethnic backgrounds.
14 citations
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February 2020 in “Stem Cells International” This study reported that a single local subcutaneous infusion of mesenchymal stromal cells from the human umbilical cord promoted wound healing, improved blood circulation, and reduced wound size in patients with chronic wounds without significant adverse effects over one year.
1057 citations
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November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
25 citations
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January 2001 in “Facial Plastic Surgery” This article reviews the history, methods, and complications of tissue expansion and serial excision for scar revision in the head and neck, and reports no new findings.
16 citations
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July 2006 in “International Journal of Oral and Maxillofacial Surgery” This case report highlights the successful use of the Bardach modification of the curved tripod flap for repairing cicatricial pressure alopecia, offering a natural appearance and effective tension distribution in scalp reconstruction.
11 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.
2 citations
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November 2023 in “Curēus” This review explores platelet-rich plasma's role in wound healing and discusses its potential as a broadly applicable therapeutic option, but it reports no new clinical results.
June 2026 in “University of Science and Technology Journal for Medical Sciences” In this study, both platelet-rich plasma gel and 1% phenytoin cream showed comparable results for wound healing in diabetic foot ulcers in rats, with PRP providing slightly advanced histological improvements; however, the differences were not statistically significant.
March 2026 in “Collagen and Leather” This study found that a newly developed supramolecular FPC hydrogel effectively promotes wound healing through its anti-inflammatory and angiogenic properties, making it a promising material for wilderness first aid due to its storage convenience, sprayability, and ability to speed up wound recovery.
January 2023 in “Open veterinary journal” This study observed that applying a cream containing secretome from Bovine Umbilical Vein Endothelial Cells promoted healing and regeneration in burn wounds in rats, particularly at a 15% concentration.
December 2002 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This review covers preoperative considerations and surgical techniques for scalp reduction in hair restoration, noting its potential to provide natural, dense coverage for large vertex defects unachievable by traditional grafting.
The researchers reported that a 4-aminopyridine-loaded gel promoted wound healing and hair follicle regeneration in burn models, suggesting it might be a promising alternative to existing burn treatments.
4 citations
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November 2025 in “Molecules” This review reports that cerium oxide nanoparticles may accelerate wound healing in animal models, but further standardized and comparative studies are needed to confirm their potential for clinical applications.
4 citations
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September 2020 in “Stem Cell Research & Therapy” In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.
1 citations
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December 2022 in “Life” This review systematically analyzed evidence on treatment options for erosive pustular dermatosis, finding that while potent topical steroids like clobetasol propionate can be effective, recurrence is common, and more robust studies are necessary for stronger recommendations.
This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.
79 citations
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January 2019 in “International Journal of Molecular Sciences” This study characterized the inflammatory response in a murine burn model, revealing similarities to human burns and supporting the model's use in testing therapies for burn complications.
21 citations
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August 2020 in “Stem Cell Research & Therapy” This meta-analysis suggests that stem cell therapy may reduce burn wound area and improve healing-related factors in preclinical models, indicating potential for future clinical studies on burn treatment.
13 citations
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March 2020 in “Acta veterinaria Scandinavica” This study found that wounds in dogs treated with allogeneic adipose-derived mesenchymal stem cells showed faster and improved healing compared to wounds receiving conventional treatment.
2 citations
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October 2025 in “Chinese Medicine” This review article summarized the design, synthesis, and application of innovative delivery systems for berberine, highlighting their potential to enhance wound healing through improved bioactivity and bioavailability, particularly in challenging conditions like diabetic and infected wounds.
December 2025 in “Journal of Clinical Medicine” In this case study, the researchers reported that surgical debridement combined with targeted dermatological and antimicrobial therapy effectively managed chronic lower-limb wounds in a patient with keratitis-ichthyosis-deafness syndrome, underscoring the importance of a multidisciplinary approach in treating this rare condition.
April 2025 in “Frontiers in Bioengineering and Biotechnology” This research explores the potential of Gel-SHP hydrogels in tissue regeneration, suggesting they could contribute to new methodologies and understanding in wound healing and dermal shell formation, but results are not detailed.
October 2024 in “Biomedical Reports” In this study, BALB/c mice with burn injuries treated with SES-low or SES-low combined with a gel showed better wound healing and organization compared to placebo and common treatments like silver sulfadiazine, highlighting SES-low's effectiveness in promoting favorable healing outcomes.
48 citations
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March 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.
18 citations
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July 2007 in “Hair transplant forum international” This study reported that using platelet-rich plasma as a storage medium for hair grafts in hair restoration surgery may improve graft survival rates and accelerate healing.