Efficacy of Neutral Electrolyzed Water vs. Common Topical Antiseptics in the Healing of Full-Thickness Burn: Preclinical Trial in a Mouse Model

    October 2024 in “ Biomedical Reports ”
    Iván Delgado‐Enciso, Nomely S. Aurelien-Cabezas, Carmen Meza‐Robles, Mireya Walle‐Guillen, Gustavo A. Hernández‐Fuentes, Ariana Cabrera‐Licona, Alejandra E. Hernández-Rangel, Marina Delgado‐Machuca, Alejandrina Rodríguez‐Hernández, Oscar F. Beas-Guzmán, Citlaly Cardenas‐Aguilar, Iram P. Rodríguez‐Sánchez, Margarita L. Martínez‐Fierro, Lic. Daniel Chaviano Conesa, B.A. Paz-Michel
    TLDR Superoxidized electrolyzed solution (SES) is more effective for burn healing than common antiseptics.
    The study investigated the effectiveness of superoxidized electrolyzed solution (SES) in treating full-thickness burns in a mouse model, comparing it to common treatments like nitrofurazone and silver sulfadiazine. Results showed that SES-low, especially when combined with a gel formulation, outperformed other treatments in promoting organized wound healing and reducing inflammation. By day 32, all treatments achieved wound closure, but SES-low was the most effective in inducing favorable healing, while silver sulfadiazine was the least effective due to its pro-inflammatory effects.
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