research Pseudoxanthoma Elasticum: Progress in Research Toward Treatment - Summary of the 2012 PXE International Research Meeting
Significant progress was made in understanding PXE, but effective treatments are still needed.
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research Photobiomodulation in Dermatology: Harnessing Light from Visible to Near Infrared
Low-intensity light therapy is effective for skin healing, reducing inflammation, and treating various skin conditions.
research Effect of Laser Diode Light Irradiation on Growth Capability of Human Hair Follicle Dermal Papilla Cells
Laser diode light boosts hair follicle cell growth and certain gene expressions.
research Anti-Invasive Effects of Minoxidil on Human Breast Cancer Cells: Combination with Ranolazine
Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.
research 2-Deoxy D-Glucose Treatment Does Not Elicit a Hair Growth Response in Alopecia Areata
2-deoxy D-glucose does not help with hair regrowth in alopecia areata.
research Association Between Metabolic Syndrome and Prevalent Skin Diseases: A Systematic Review and Meta-Analysis of Case-Control Studies
People with certain skin conditions, especially androgenic alopecia, are more likely to have metabolic syndrome.
research Real-World Experience and Long-Term Evaluation of Tofacitinib in Refractory Alopecia Areata: A Prospective, Open-Label, Single-Center Study in Asian Arab Population
Tofacitinib is a promising treatment for severe alopecia areata, with many patients experiencing complete or partial hair regrowth.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Evaluation of the Safety and Effectiveness of Oral Minoxidil in Children: A Systematic Review
Low-dose oral minoxidil is safe for treating children's hair disorders.
research Severe and Refractory Hypotension After Intentional Minoxidil Overdose: A Case Report
Minoxidil overdose caused severe low blood pressure, but the patient recovered with specific treatments.
research Increase in Subcutaneous Adipose Tissue in the Frontal Scalp May Be Associated With Androgenetic Alopecia and Metabolic Syndrome
Thicker scalp fat may link hair loss with metabolic syndrome.
research The Role of Mitochondria in Skin Aging
Mitochondrial dysfunction contributes to skin aging and hair loss.
research Ichthyoses
Ichthyoses are skin disorders causing scales, with treatment depending on type and severity.
research Clinical and Metabolic Characteristics of Males With Early-Onset Androgenetic Alopecia
Altered hormones and insulin resistance are common in young men with early hair loss and linked to more severe cases.
research The Use of Minoxidil in Diseases Associated with Hair Loss
Minoxidil, a medicine initially for high blood pressure, can stimulate hair growth and is promising for treating hair loss, but it may cause side effects like itching and dizziness.
research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Mechanistic Target of Rapamycin (mTOR) Expression Is Increased in Acne Patients' Skin
Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
research Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial-Mesenchymal Interactions
Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
research Transport of Biotin in Human Keratinocytes
Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
research The PDE4 Inhibitor, Apremilast, Suppresses Experimentally Induced Alopecia Areata in Human Skin In Vivo
Apremilast may help treat hair loss in alopecia areata.
research Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse
Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
research Photobiomodulation for the Management of Alopecia: Mechanisms of Action, Patient Selection, and Perspectives
Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.
research Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the Brown Norway Rat
Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
research Hair-Loss Preventing Effect of Grateloupia Elliptica
Grateloupia elliptica extract may help prevent hair loss and promote hair growth.
research Minoxidil Induced Hypertrichosis in a 2-Year-Old Child
A 2-year-old boy grew excessive hair after using minoxidil for hair loss, but it improved when the treatment stopped.
research Argan (Argania Spinosa) Press Cake Extract Enhances Cell Proliferation and Prevents Oxidative Stress and Inflammation of Human Dermal Papilla Cells
Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.
research Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/β-Catenin Pathway in Dermal Papilla Cells
Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Pilot Study: Autologous Platelet-Rich Plasma Used in a Topical Cream for Facial Rejuvenation
Topical PRP cream may improve facial skin by boosting collagen.