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Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.