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Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Different types of stem cells and their environments are key to skin repair and maintenance.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Hair follicle stem cells could be used to treat the skin condition vitiligo.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Collagen XVII is important for skin aging and wound healing.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

CD4+ skin cells may be precursors to basal cell carcinoma.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.