2 citations
,
July 2018 in “Journal of Cosmetic Dermatology” This commentary discusses how common latent viruses might contribute to male-pattern baldness through mechanisms involving transcription factor deficiency and overexpression of specific proteins, based on a concept called microcompetition; it reports no new research results.
July 2020 in “European urology open science” Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.
93 citations
,
February 2009 in “Annals of the New York Academy of Sciences” This review describes the roles of 5α-reductase isozymes in prostate development and pathology and reports no new clinical results.
46 citations
,
September 2010 in “Southern Medical Journal” This review discusses low-level light therapy for androgenetic alopecia and female pattern hair loss, noting minimal clinical evidence on its efficacy and the need for more controlled studies.
11 citations
,
December 2018 in “Assay and Drug Development Technologies” This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.
3 citations
,
June 2021 in “Cosmetics” This study found that sulforaphane may help alleviate hair loss by increasing hair count after 18 weeks of use and enhancing the expression of a DHT-degrading enzyme in cellular models.
85 citations
,
October 2006 in “Current opinion in cell biology” This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
48 citations
,
June 2014 in “Neurobiology of Disease” This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.
31 citations
,
March 2018 in “Frontiers in Immunology” This article reviews the complexities and challenges in classifying systemic lupus erythematosus and the problematic role of the anti-dsDNA antibody as a biomarker, without presenting new experimental findings.
26 citations
,
September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.
25 citations
,
September 2006 in “Birth Defects Research” This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.
24 citations
,
January 2015 in “Annals of Dermatology” In this study, herbal extracts commonly used in traditional medicine were observed to significantly increase the proliferation of human dermal papilla cells, suggesting potential as alternative therapies for enhancing hair growth.
23 citations
,
February 2020 in “PLOS genetics” This study found that biallelic LSS mutations lead to congenital hypotrichosis and cataracts, with each tissue-specific loss of function observed in mouse models.
22 citations
,
October 2011 in “Bone” This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.
22 citations
,
October 2001 in “Biochemical Pharmacology” This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.
19 citations
,
March 2010 in “Bioorganic & Medicinal Chemistry Letters” This study evaluated curcumin analogues as potential inhibitors of 17β-HSD3 in rat and human models, but it does not report new clinical findings.
18 citations
,
October 2020 in “PLoS ONE” This study highlights the interconnected emotional distress between patients with end-stage COPD and their family caregivers, emphasizing that both parties' functional and emotional variables influence each other's distress.
15 citations
,
March 2021 in “Rheumatology and Immunology Research” The CSTAR registry, the largest in China for SLE, reports more than 25,000 patients registered since 2009, detailing demographics, clinical characteristics, and providing data for future studies.
14 citations
,
June 2021 in “Expert Opinion on Therapeutic Patents” This review discusses various Wnt pathway modulators developed between 2014 and 2020, highlighting their potential as treatments for diseases like cancer and osteoarthritis, but reports no new clinical results.
14 citations
,
October 2000 in “Genomics” This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.
13 citations
,
August 2020 in “Frontiers in Immunology” This review explores the expression of Perforin by gamma delta T cells in human skin and its role in cytotoxicity but reports no new experimental results.
6 citations
,
September 2024 in “Discover Psychology” This study observed that men who conform more strongly to traditional masculinity norms are likelier to undergo cosmetic surgery as a way to assert power, success, dominance, and sexual success.
5 citations
,
May 2023 in “Frontiers in immunology” This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.
4 citations
,
June 2025 in “Frontiers in Immunology” This review discusses the role of the BAFF system in autoimmune diseases and highlights its therapeutic potential, emphasizing the need for disease-specific clinical trials to improve treatment strategies.
2 citations
,
January 2025 in “Pharmaceutical Research” This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.
1 citations
,
November 2025 in “Frontiers in Immunology” This review explores the complex role of the Innate Immune System in rheumatoid arthritis, highlighting gaps in understanding its functions and interactions with the Adaptive Immune System, offering insights into potential biomarkers and therapeutic strategies for this challenging autoimmune condition.
February 2026 in “Journal of the Korean Society of Cosmetology” This study found that among older adults in Korea, satisfaction with scalp and hair-care services and perceived effectiveness in managing hair loss were the strongest predictors of their intention to continue using these services, with self-esteem and relational factors also contributing positively.
December 2025 in “Journal of World Economy” In this study, original natural organic cosmetics with a natural index of ≥ 90% and efficacy patents increased purchase intention and reduced promotional dependency in the US market.