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This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.

This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.

This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.

The researchers observed that normal murine hair follicles are direct targets for melatonin, with receptor expression varying throughout the hair cycle, suggesting melatonin's role in hair cycle control.

This study demonstrated that genetic markers can predict human ear morphology with moderate to good accuracy, potentially aiding forensic identification in crime scene investigations where traditional DNA matches are unavailable.

Flutamide-induced hypospadias in rats slows down early wound healing.

The study found that hybrid nanoparticles incorporating exosomes with cationic liposomes 2X3-DOPE significantly improved the delivery of both messenger RNA and small interfering RNA to rat cardiac mesenchymal stem cells in vitro, achieving up to 100% transfection efficiency for small interfering RNA.

In this study, researchers analyzed skin samples from Dorper sheep to identify 395 differentially expressed long non-coding RNAs (lncRNAs) linked to hair follicle growth phases, suggesting these lncRNAs may play a role in the regulation of hair shedding through pathways like estrogen and PI3K-Akt signaling.

This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.

This study found that overexpressing Rps14 in supporting cells promoted hair cell regeneration in the organ of Corti by facilitating cell proliferation and differentiation.

This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.

This study reported that high cholesterol levels were linked to increased prostate cancer risk, while selenium supplementation affected gene expression, suggesting nutritional and clinical factors might influence prostate cancer risk and biology.

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

This study shows that macrophage-induced TNF signaling can activate hair follicle stem cells and promote new hair follicle formation after wounding by regulating AKT/β-catenin pathways.

This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.

This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.

This study suggests that TGF-alpha may function in an autocrine or juxtacrine manner rather than promoting cell proliferation during hair growth cycles in ferrets and sheep.

This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.

This review provides an analysis of topical treatments with clinically proven efficacy for managing hyperpigmentation and concludes that the most effective approach is using combined therapies that target multiple aspects of skin pigmentation physiology.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.

This study found that IL-17A-producing γδ T cells play a key role in bone fracture healing by promoting bone formation, with deficiencies leading to impaired repair in mice.

This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.

This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.

This review explores the potential of periodontal ligament stem cells for regenerative therapy in periodontium, despite challenges due to their rarity, and reports no clinical results.

This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.

This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.

In this study, researchers developed a method to differentiate human iPSCs into cells that can generate all lineages of hair follicles, potentially aiding treatments for hair loss and skin disorders.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.