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Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Mutations in certain receptors can cause diseases and offer new treatment options.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.