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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Dutasteride and finasteride affect different cell types differently.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Blocking testosterone speeds up wound healing in males.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Blocking testosterone speeds up wound healing in males.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

Early hormones shape sex-specific differences in rat glands.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.