Search

everythinglearnresearchcommunity

for

Search:↓

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Testosterone helps human pancreatic cells increase insulin release.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.