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Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Better hair loss models needed for research.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.