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Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Androgens may block hair growth signals, targeting this could treat hair loss.

Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Male pattern baldness involves hormones and cell signals affecting hair growth.

New treatments for PCOS focus on managing symptoms and improving fertility.

Hormones and genes affect hair growth and male baldness.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.

Androgens can help prevent memory problems caused by apoE4.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.