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TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.

DHT stops hair regrowth in mice, similar to human hair loss.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens slow hair growth by altering Wnt signaling in balding cells.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Androgens may block hair growth signals, targeting this could treat hair loss.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Hura crepitans and its compound daphne factor F3 may help treat hair loss by blocking a specific hair growth inhibitor.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Excess androgens may cause PCOS, not just be a symptom.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

SM-215 promotes hair growth by improving the environment around hair follicles.

Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.

Platycarya strobilacea extract is a strong antioxidant that can grow hair better than minoxidil.