Clinical Evaluation of Women Presenting with Low Libido and Determination of Whether Androgen Therapy Might Be Appropriate

The 2006 document reviews the complex nature of female sexual dysfunction (FSD) and low libido, suggesting that androgen therapy may be beneficial for women with androgen deficiency. It emphasizes the need for a comprehensive clinical evaluation, including physical examinations and laboratory tests, to identify the underlying causes of FSD. The document notes that androgen therapy, while potentially beneficial for mood, well-being, libido, and bone density, carries risks such as acne, hirsutism, and more serious health concerns, and should be prescribed cautiously. It also mentions that testosterone therapy may be considered for women with low androgen levels and clinical deficiency symptoms, but long-term safety data is lacking. Nonpharmacologic treatments are recommended alongside androgen therapy, which is still under clinical evaluation with no approved testosterone formulations for FSD in the United States.