research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
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research Maternal Nutrition at Conception Modulates DNA Methylation of Human Metastable Epialleles
A mother's diet at conception can cause lasting genetic changes in her child.
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Postoperative Chemotherapy and Tamoxifen Compared with Tamoxifen Alone in the Treatment of Positive-Node Breast Cancer Patients Aged 50 Years and Older with Tumors Responsive to Tamoxifen: Results from the National Surgical Adjuvant Breast and Bowel Project B-16
Adding chemotherapy to tamoxifen improves survival for older breast cancer patients with positive nodes.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Wnt1/β-Catenin Injury Response Activates the Epicardium and Cardiac Fibroblasts to Promote Cardiac Repair
Wnt1/βcatenin signaling is crucial for heart repair after injury.
research Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss
FPHL affects hair density and diameter, causing visible hair loss in older women.
research Roles of Msx and Dlx Homeoproteins in Vertebrate Development
Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012
Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research Evaluation and Treatment of Male and Female Pattern Hair Loss
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
research Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation
Lactate production is important for activating hair growth stem cells.
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
research Why Some Women Look Young for Their Age
Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
research Independent Genomewide Screens Identify the Tumor Suppressor VTRNA2-1 as a Human Epiallele Responsive to Periconceptional Environment
The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
research S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents
Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version
Use minoxidil for hair loss treatment; assess results after 6 months.
research Do Men's Faces Really Signal Heritable Immunocompetence?
Masculine facial features may not reliably indicate heritable health, and more research is needed.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research Alopecia Areata: Pathogenesis And Treatment
No single treatment is consistently effective for alopecia areata, and more research is needed.
research Dermatology Position Paper on the Revision of the 1982 ACR Criteria for Systemic Lupus Erythematosus
The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.
research Reproductive Dysfunction in Women With Epilepsy: Recommendations for Evaluation and Management
Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
research Somatosensory Organization and Behavior in Naked Mole-Rats: Peripheral Structures, Innervation, and Selective Lack of Neuropeptides Associated with Thermoregulation and Pain
Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
research Follicular Miniaturization in Female Pattern Hair Loss: Clinicopathological Correlations
Hair loss severity relates to increased miniaturization in female pattern hair loss.
research Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride
Finasteride improves hair loss in women with hyperandrogenism.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.