Encephalitis Lethargica Due to Epstein–Barr Virus Infection

The document reports on a study that investigated the effects of finasteride on 10 patients with Tourette syndrome (TS). The study found that finasteride significantly reduced the severity of global symptoms, total tics, motor tics, and phonic tics, with p-values less than .0001, according to the Yale Global Tic Severity Scale (YGTSS). Additionally, for the 6 patients with obsessive-compulsive symptoms, there was a significant reduction in the total scores and compulsion subscale scores of the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), with p-values of .028. However, there was no significant reduction in the obsession subscale scores (p = .068). The study concludes that finasteride may be a potential therapeutic option for adult male patients with TS and suggests further controlled studies to confirm its effectiveness.