research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
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90-120 / 297 resultsresearch FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Metabolic Syndrome and Skin Diseases
Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research TOR Tour to Auxin
The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research A Review on the Chemical Constituents and Pharmacological Efficacies of Lindera Aggregata (Sims) Kosterm
Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research Rosmarinus Officinalis and Skin: Antioxidant Activity and Possible Therapeutic Role in Cutaneous Diseases
Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Quercetin and Polycystic Ovary Syndrome
Quercetin may help improve symptoms of polycystic ovary syndrome.
research The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review
Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Roles of miRNAs in Sheep Hair Follicle Development
Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Current Progress on Cordyceps Militaris, Its Metabolite Function, and Production
Cordyceps militaris is a promising, cost-effective medicinal fungus with health benefits and efficient production methods.
research Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids
Cannabidiol shows promise as an effective treatment for acne.
research Nigella Sativa And Its Nano-Mediated Approach Toward Management Of Neurodegenerative Disorders: A Review
Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.
research A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch
The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Mitochondrial Dysfunction in Metabolic Syndrome and Inflammatory Skin Disease
Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.