February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization analysis to find a significant causal relationship between high fasting insulin levels and androgenetic alopecia, while identifying potential core genes and metabolic pathways that could mediate this link.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.
In this study, aqueous and aqueous-alcoholic extracts of Ajuga reptans showed promising hepatoprotective and wound-healing properties, with significant effects observed in experimental models, suggesting potential for development into official medicinal products pending further research.
November 2024 in “Journal of Functional Foods” In this study, APC collagen peptides were observed to enhance hair elasticity and gloss in human hair follicles by increasing amino acid and lipid component levels, suggesting their potential benefits for improving hair qualities.
This study evaluated a newly formulated herbal hair growth serum, containing natural ingredients like olive oil, hibiscus, and amla, which showed promising preliminary results in improving hair growth, strength, and overall hair health.
October 2024 in “UNESP Institutional Repository (São Paulo State University)” This study investigated the effects of ammonium thioglycolate and amino methylpropanol hair straightening followed by permanent coloring, finding significant physical and chemical changes to both the cuticle and cortex of hair fibers.
This study in Saudi Arabia found that nearly half of participants had low knowledge about thyroid disease risk factors and symptoms, suggesting a need for improved health education programs to enhance public awareness in the Al-Baha region.
September 2024 in “Brazilian Journal of Hair Health” This study found that four months of oral nutrient supplements improved hair density by 16-21% and caliber by 18-22% in men and women with pollution-related hair loss, addressing oxidative damage without using finasteride, antiandrogens, or minoxidil.
September 2024 in “Meditsinskiy sovet = Medical Council” This source reports that biotin, a water-soluble vitamin B7, may benefit skin, hair, and nail health, including various types of alopecia, without the risk of hypervitaminosis even at high doses.
July 2024 in “International journal of agriculture and food sciences research.” This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.
July 2024 in “Experimental Dermatology” This study suggests that APC collagen peptides may accelerate hair growth and promote overall hair health by enhancing cellular proliferation and activating specific signaling pathways in human and mouse models.
June 2024 in “Research Square (Research Square)” In this study, researchers identified nine FDA-approved drugs that activate the Wnt signaling pathway, with Aminoacridine, especially when combined with Minoxidil, showing promising effects on hair and nail growth in mice, suggesting potential treatments for hair and nail loss pending further clinical trials.
June 2024 in “Indian Journal of Veterinary Medicine” In this case report, a one-year-old male dog with demodicosis, confirmed by the presence of Demodex canis and Staphylococcus bacteria, was successfully treated using ivermectin, amitraz, cephalexin, and vitamin supplements with liver extract.
May 2024 in “BMC veterinary research” In this study, researchers observed that metabolite expression patterns, including sugars, lipids, amino acids, and nucleotides, affect hair follicle growth in cashmere goats, with feeding practices potentially influencing these cycles via hormone and vitamin levels.
May 2024 in “Journal of molecular structure” This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.
March 2024 in “Nutrients” This study found that individuals with Alopecia Areata had distinct gut microbiome characteristics, including reduced species richness and specific microbial biomarkers, suggesting a potential link with oxidative stress.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that certain tandem repeats predict darker hair color across diverse ancestry groups and can contribute to a polygenic score for hair color, independent of SNP variation.
February 2024 in “BMC genomics” This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.
This study assessed the environmental impact of the drug finasteride on Daphnia magna, finding that both acute and chronic exposure impaired development and reproduction, affected gene expression and metabolism, and altered lipid profiles, highlighting the need to understand pharmaceutical impacts on aquatic ecosystems.
January 2024 in “International Journal of Veterinary Sciences and Animal Husbandry” This case report described a 4-year-old Pomeranian dog diagnosed with Demodex canis infestation, which showed complete recovery from skin lesions and other symptoms after a 35-day treatment regimen that included ivermectin injections, amitraz baths, and oral antibiotics.
This paper explores the diverse patterns and social significance of Black hair, approaching it as an art form, mathematical pattern, and ethnomathematic entity, and seeks to dispel myths while highlighting its vast possibilities.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
September 2023 in “Jurnal Ilmu Kesehatan Hewan” This case report describes a Balinese breed dog diagnosed with demodecosis and malasseziosis, which improved after 30 days of treatment including amitraz, ketoconazole, and supportive therapies. The findings suggest that consistent treatment and environmental management can aid in recovery from these skin conditions in dogs.
This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.
In this study, researchers successfully cloned the KAP24.1 gene from sheep to analyze its expression in skin and hair follicles, finding that Mountain-type Hetian sheep showed the highest levels of expression and that androgen concentration significantly influenced KAP24.1 protein expression.
April 2023 in “Journal of Investigative Dermatology” This study found that human TMEM2 does not function as a hyaluronidase but is involved in regulating hyaluronan metabolism.
April 2023 in “Journal of Investigative Dermatology” In this study, Aminoacridine, Abemaciclib, and the combination of Aminoacridine with Minoxidil showed potential for effective hair regeneration by activating Wnt/β-catenin signaling in animal experiments.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this case report, an 8-month-old pug with poor health and skin issues was treated effectively for mixed infections, resulting in complete recovery after 60 days.
October 2022 in “Research, Society and Development” This review highlights that while vitamin and mineral supplementation shows limited impact on hair loss treatment, deficiencies in iron, zinc, and vitamin D are common among patients with telogen effluvium.
September 2022 in “Journal of The American Academy of Dermatology” This case report describes a 58-year-old woman with telogen effluvium linked to COVID-19 whose hair loss symptoms greatly improved after using a specific hair care routine for 30 days.