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Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

A child's chronic use of Senna caused liver damage and a severe decrease in blood cells, but improved after stopping Senna and getting treatment.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

New methods to test hair growth treatments have been developed.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

Increasing alkaline phosphatase in human skin cells helps to grow more hair.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Histone H4, released by cells exposed to colchicine, can cause hair loss by inhibiting cell growth and enzyme activity.

Tetrathiomolybdate reduces hair growth marker in skin cells by boosting harmful oxygen molecules, but effects can be reversed.

Glyoxylic acid straighteners cause more protein loss but have similar hair strength effects as traditional alkaline straighteners.

Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.

Joint replacement surgery normalized high alkaline phosphatase levels in a patient with severe osteoarthritis.

Alkaline hair relaxers damage hair, but cationic and non-ionic polymers can help reduce this damage.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

Shampoo pH can affect hair health, with alkaline shampoos potentially causing damage and acidic shampoos reducing frizz.

Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.

Human skin cells can create new hair follicles when transplanted into mice.

Keratin peptides can change hair shape gently without harsh chemicals.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.