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This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This review analyzes the role of silver nanoparticles in wound healing, highlighting their antimicrobial, anti-inflammatory, and tissue-regenerating properties, and emphasizes the need for further research to optimize formulations and ensure safety.

This review discusses recent advances in protein immobilization on bacterial cellulose for various biomedical uses and reports no new clinical results.

This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.

This review discusses recent advancements in responsive-hydrogel dressings for diabetic wound healing, highlighting their design, responsiveness, and degradation behavior, and evaluating their potential advantages and limitations in clinical applications.

This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.

This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.

This study found that modifying biphasic calcium phosphate/poly(methyl methacrylate) bone cement with human hair keratin improves its hydrophilicity, mechanical properties, and supports bone repair in rats, indicating potential for orthopedic applications.

This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This study reported that abietic acid, derived from pine rosin, showed antimicrobial effects and reduced biofilm biomass in laboratory tests against microorganisms like Staphylococcus aureus and Candida albicans, suggesting potential further applications for skin infections.

In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.

This review examined the potential effects of Kampo medicine Hangeshashinto on oral mucositis, highlighting that several natural products in its composition may inhibit intracellular AGEs, reduce inflammation from extracellular AGEs, and suppress cytotoxicity in stomatitis.

This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.

The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.

This review discusses recent advancements in the development and use of polymer-based nanohydrogels for topical drug delivery, noting their potential to enhance drug loading, release control, and skin penetration for treating dermatological conditions.

This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.

This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.

This review highlights how cyclodextrin-polysaccharide hybrids can advance drug delivery and environmental cleanup by improving the solubility and stability of hydrophobic molecules, serving as promising platforms for biomedical applications and efficient sorbents for wastewater treatment.

This review discusses the properties and bioextraction methods of chitin and chitosans, emphasizing their potential use in eco-friendly cosmetic manufacturing and reports no new experimental findings.

This literature review discusses recent advances in using essential oils and their components in cosmetic products, highlighting their diverse benefits and challenges in formulation due to varying chemical profiles, as well as addressing safety considerations for these natural ingredients.

This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.

This review examines the phytochemical constituents and pharmacological effects of licorice, discussing its potential health benefits and side effects without reporting new clinical results.

This review discusses the challenges of skin graft acceptance and examines current strategies and alternatives for full-thickness skin replacement and repair, noting that immunological rejection remains a significant hurdle.

This review discusses advancements and challenges in bioengineered scaffolds for wound healing but presents no new experimental findings, highlighting their potential and need for further development.

In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.

This study explored the expression and potential functions of long non-coding RNAs in the skin pigmentation of Koi carp, revealing their involvement in pigmentation and differentiation mechanisms.

This review article highlights recent advancements in smart hydrogels as promising solutions for diabetic wound management, emphasizing their ability to respond to wound environments and deliver targeted therapies, while addressing limitations of traditional dressings.

This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.