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    Glossary AIM2 inflammasome

    protein complex detecting foreign DNA, triggering immune responses

    The AIM2 inflammasome is a protein complex in the immune system that detects foreign DNA inside cells, such as from viruses or bacteria. When AIM2 senses this DNA, it activates a series of responses that lead to inflammation and the destruction of the infected cell, helping to protect the body from infections.

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    Research 30 of 58

    1. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    2. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    3. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    4. Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair Burns & Trauma · 2026
    5. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    6. Inflammasome Proteins Are Reliable Biomarkers of the Inflammatory Response in Aneurysmal Subarachnoid Hemorrhage Cells · 2024 · 4 citations
    7. Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products Frontiers in Pharmacology · 2024 · 18 citations
    8. Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology Hair transplant forum international · 2012 · 1 citations
    9. Cell death in skin function, inflammation, and disease Biochemical Journal · 2022 · 12 citations
    10. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    11. Quoi de neuf en recherche dermatologique ? Annales de Dermatologie et de Vénéréologie · 2011 · 2 citations
    12. Stem cell dynamics, migration and plasticity during wound healing Nature Cell Biology · 2018 · 211 citations
    13. Choreographing Immunity in the Skin Epithelial Barrier Immunity · 2019 · 57 citations
    14. Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration Frontiers in public health · 2022 · 4 citations
    15. Wedelolactone, a natural coumestan with multiple pharmacological effects Frontiers in Pharmacology · 2026
    16. <i>Malassezia</i> and the Asian menopausal skin 2025
    17. The role of the skin microbiome in wound healing Burns and trauma · 2023
    18. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    19. The role of multiomics in revealing the mechanism of skin repair and regeneration Frontiers in Pharmacology · 2025 · 4 citations
    20. Diverse mechanisms for endogenous regeneration and repair in mammalian organs Nature · 2018 · 172 citations
    21. The Immune Functions of Keratinocytes in Skin Wound Healing International Journal of Molecular Sciences · 2020 · 147 citations
    22. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020 · 18 citations
    23. New insights into inflammatory memory of epidermal stem cells Frontiers in immunology · 2023 · 2 citations
    24. Meta-Analysis of Gene Expression Reveals the Core Transcriptomic Profile of Lesional Scalp in Alopecia Areata Dermatology and Therapy · 2025
    25. Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · 2025
    26. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    27. Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin International journal of molecular sciences · 2021 · 9 citations
    28. Commonalities Between COVID-19 and Radiation Injury Radiation Research · 2020 · 18 citations
    29. Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation Antibiotics · 2024 · 7 citations
    30. Mechanisms of autophagy and their implications in dermatological disorders Frontiers in Immunology · 2024 · 6 citations