8 citations
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January 2016 in “Annals of Dermatology” This study found that the ALAVAX complex, containing 5-ALA and GHK peptide, may increase hair count in male pattern hair loss patients over 6 months without adverse events.
April 2026 in “American Journal of Dermatopathology” This study identified a new dermoscopic feature, plexiform erythema, in lichen planopilaris lesions, suggesting it may indicate active disease and the potential need for more aggressive treatment.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study suggests that decreased PPARgamma function may trigger the pathogenesis of lichen planopilaris, and PPARgamma-targeted therapy could be a potential treatment method.
July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” AA-PRP injections significantly promote hair growth but need better study design for clear efficacy.
May 2024 in “Journal of the Egyptian Women's Dermatologic Society /Journal of the Egyptian Women's Dermatologic Society” In this split-scalp study, researchers observed that combining fractional CO2 laser and PRP treatment was significantly more effective in improving hair parameters in women with female pattern hair loss than using each intervention alone or placebo.
This study suggests that platelet-rich plasma may provide short-term improvement in hair density for female pattern hair loss, but results varied and more rigorous trials are needed to establish optimal protocols.
November 2024 in “Cureus” The authors reported a case of significant scalp edema accompanying lichen planopilaris in a middle-aged woman, suggesting a potential new variant of edematous scalp conditions as a reaction to scarring alopecia.
4 citations
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November 2016 in “Journal of Cutaneous Pathology” This letter discusses three plasmacytoid dendritic cell-related parameters that may help differentiate lupus alopecia from lichen planopilaris, but it reports no new study results.
7 citations
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September 2014 in “European Journal of Dermatology” This study found a significant positive correlation between hair thickness and growth rate, with a notably slower growth rate observed in men with male pattern hair loss compared to healthy controls.
January 2026 in “Dermatology Practical & Conceptual” This study reported that diffuse lichen planopilaris significantly impairs quality of life in Moroccan patients, with trichodynia and hair quality changes most affecting daily functioning and leisure activities.
44 citations
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January 2011 in “Journal of Cutaneous Pathology” This study introduces the "HoVert" technique, which generates both vertical and horizontal sections from a single biopsy to effectively differentiate lichen planopilaris from discoid lupus erythematosus in alopecia cases.
1 citations
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January 2017 in “대한피부과학회지” This study observed that male pattern hair loss patients are getting diagnosed earlier and presenting with milder forms, possibly due to early puberty, and noted frequent familial predisposition and comorbidities like seborrheic dermatitis.
January 2026 in “Clinical Case Reports” This review discusses the etiology of moth-eaten alopecia patterns in lichen planopilaris and emphasizes the importance of early diagnosis and treatment to prevent permanent scarring, offering no new empirical findings.
This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.
1 citations
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February 2013 in “Clinical pediatrics” The baby’s hair loss was due to a rare genetic condition, not treatable by usual methods.
15 citations
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May 2016 in “Archives of Dermatological Research” This study found significantly higher levels of the protein ULBP3 in patients with alopecia areata incognita compared to other hair loss conditions and healthy controls, suggesting ULBP3's potential as a diagnostic marker for AAI.
March 2020 in “Clinical research in dermatology” This report describes two unusual cases of lichen planopilaris in Caucasian patients, detailing features suggestive of folliculotropic mycosis fungoides and an overlap with systemic lupus erythematosus.
July 2025 in “Case Reports in Dermatology” This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.
8 citations
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September 2021 in “Facial plastic surgery & aesthetic medicine” This systematic review found that low-level light/laser therapy showed a positive effect in treating male and female pattern hair loss without side effects, as reported by all analyzed randomized controlled trials.
4 citations
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February 2014 in “Proceedings of SPIE” This review discusses the diverse applications of low-level laser therapy in aesthetic dermatology, especially for managing alopecia, but notes that comprehensive literature on its effectiveness is lacking.
4 citations
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January 2011 in “Annals of Dermatology” This article discusses the role of HR gene mutations in differentiating atrichia with papular lesions from alopecia universalis, but presents no new experimental results.
2 citations
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June 2024 in “Frontiers in Plant Science” This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.
May 2023 in “Pharmaceuticals” In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.
9 citations
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June 2020 in “Tissue Engineering and Regenerative Medicine” This study found that applying HHORSC exosomes may enhance the hair inductivity of dermal papilla cells, potentially improving treatments for hair loss.
16 citations
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January 2019 in “Neuropsychobiology” This study found that individuals with lichen planopilaris reported lower quality of life and self-esteem and higher depression scores compared to healthy controls.
November 2021 in “Authorea (Authorea)” This case report suggests that platelet-rich plasma and hair transplantation may trigger or worsen the progression of cutaneous pseudolymphoma to lymphoma, particularly in patients with a family history.
This article reports a rare case of a postmenopausal woman with coexisting lichen planus pigmentosus and classic lichen planopilaris, alongside a review of related literature.
June 2017 in “Journal of The American Academy of Dermatology” Women in Australia report different signs of facial aging compared to women in the US, UK, and Canada; men with Lichen planopilaris often have hormonal abnormalities and thyroid disease.
May 2025 in “International Journal of Molecular Sciences” In a mouse study, Fr2 from Platycladus orientalis L. significantly enhanced hair growth, suggesting its potential as a natural therapeutic agent for hair regeneration.
10 citations
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January 2010 in “Journal of cosmetic and laser therapy” This article describes a non-blinded study investigating low level laser therapy for seven patients but reports no new clinical findings.