research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
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research Cell Type-Specific Actions of Thyroid Hormones in Nonalcoholic Steatohepatitis and Liver Fibrosis
Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Ovarian Hyperthecosis in Adolescent Females: Two Case Reports and a Review of the Literature
Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
research Hirsutism: Diagnosis and Treatment
The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
research Endocrine Disorders and Infertility
Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
research Discovery of Nonsteroidal Androgens
Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
research Human Hair Follicles Can Taste: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2
Activating a bitter taste receptor in hair follicles can stop hair growth by increasing a specific growth factor.
research Is Seborrhea a Sign of Autonomic Impairment in Parkinson's Disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Treatment Guidelines in Adult Women: Effectiveness of Hormonal Therapy in Treating Acne Vulgaris
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases
Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.
research Cardiovascular Profile of Pharmacological Agents Used for the Management of Polycystic Ovary Syndrome
Medications for PCOS don't seem to raise heart disease risk.
research Hirsutism II: Treatment
The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.
research Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters
Sandalore® improves hair growth and quality in people with hair loss.
research Peroxisome Proliferator Activated Receptors Gamma Serum Levels and Gene Polymorphism in Frontal Fibrosing Alopecia: A Case-Control Study
Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
research Non-Hormonal Treatment Options for Regulation of Menstrual Cycle in Adolescents with PCOS
Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research GLP-1 Agonists and Hair Loss: A Call for Further Investigation
More research is needed to understand if GLP-1 agonists affect hair health.
research Targeting Pharmacological and Nanotechnology Based Therapeutics for Management of Hirsutism: A Comprehensive State-of-the-Art
New treatments for excessive hair growth in women, including advanced drugs and nanotechnology, show promise for better results.
research On Photo-Stability of Oxybenzone
Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.
research Clinical Snippets: Stabilization of Vitamins C and E, Hedgehog Pathway Agonists, Atopic Dermatitis, Lentigo Maligna Melanoma, and Relaxin-Deficient Mice
Ferulic acid helps stabilize vitamins C and E for better skin protection from the sun, certain compounds may promote hair growth, atopic dermatitis patients have lower skin defense molecules, older men are more likely to get a type of skin cancer, and a substance called relaxin may prevent age-related skin thickening.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin
Topical retinoids effectively improve photodamaged skin.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research Review: Dutasteride, Fesoterodine, and Finasteride Are Beneficial for Lower Urinary Tract Symptoms in Older Patients
Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.