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In this study, researchers found that girls aged 4-8 years with isolated premature thelarche had significantly advanced bone age, with obesity and elevated serum IGF-1 SDS and DHEAS SDS being key independent risk factors.

This study found that girls with isolated premature thelarche, confirmed by GnRH stimulation test, aged 4-8 years, may have significantly advanced bone age, with obesity and serum IGF-1 and DHEAS levels being key risk factors.

This study suggests that the exercise-induced cytokine IL-15 can improve wound healing in aged skin, along with previously reported benefits on skin structure and mitochondrial function.

The study found that for positive-node breast cancer patients aged 50 and older, adding chemotherapy to tamoxifen significantly improved disease-free survival compared to tamoxifen alone.

The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study found that nearly 80% of Finnish adults aged 70 to 93 had at least one skin disease requiring treatment, with men more affected than women.

In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.

This study found that the prevalence of PCOS among Australian women aged 16-29 was 12% using NIH criteria, with fertility concerns being the most distressing aspect for those diagnosed.

This study reported that finasteride 1 mg significantly improved hair growth in men aged 41 to 60 with predominantly vertex male pattern hair loss over 24 months compared to placebo.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

In this study, acne and hirsutism in women were associated with a higher prevalence of polycystic ovary syndrome compared to those without these conditions.

Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.

This study found non-melanoma skin cancer in 7.2% of elderly residents in long-term care facilities in Berlin, highlighting the need for more routine skin cancer screenings in these settings.

In this study, the prevalence of insulin resistance in reproductive-aged Thai women with polycystic ovary syndrome was found to be 20%, with age, waist circumference, acanthosis nigricans, and dyslipidemia as significant predictors.

In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.

This study concluded that hair-derived stem cells from older donors may offer a promising alternative for autologous corneal endothelial replacement, potentially benefitting patients of various age groups.

This case report highlights the importance of considering exogenous androgen exposure, such as transdermal testosterone cream used by a partner, in the diagnosis of virilization among women.

This article reviews the causes and diagnosis of hyperandrogenism, highlighting its impact on female fertility and the metabolic risks associated with PCOS, but it provides no new clinical results.

This study reported that atelocollagen enhances collagen synthesis and reduces oxidative stress in aged skin by increasing glycine uptake through GlyT1, resulting in improved skin elasticity and collagen density in aged mice, with effects superior to glycine alone.

This study observed that consuming 50g of cheonggukjang daily for 3 months improved eyebrow length, thickness, and reduced damage in middle-aged women compared to controls, although the number of eyebrows did not change.

In this large retrospective study, low-dose finasteride for androgenetic alopecia was associated with an increased risk of erectile dysfunction at one and three years among men aged 18-45.

No results are reported in this dataset abstract, which details supplementary materials for a systematic review and meta-analysis on oral Janus kinase inhibitors' effectiveness and safety in children with alopecia areata, aiming to enhance transparency and interpretation of the main article's findings.

In this systematic review and meta-analysis on participants aged 12 and under with alopecia areata, the authors provide supplementary tables and figures, including pooled outcomes for hair regrowth and safety of oral Janus kinase inhibitors, supporting the main findings on their effectiveness and safety.

This study assessed women in Bangladesh and found that those with PCOS had markedly higher rates of depression, anxiety, stress, and insomnia compared to those without the condition, with rural women showing higher anxiety and insomnia.

In this study, researchers investigated age-related hearing loss in advanced-age CBA/CaJ mice and found combined cochlear damage from chronic sound exposure and metabolic changes linked to oxidative stress, which may require addressing both etiologies for prevention and treatment.

In this study, aged mice showed better regenerative skin outcomes than young mice, linked to a specific fibroblast subpopulation and enhanced signaling interactions that promote regeneration. EREG treatment improved young mice's skin regeneration, suggesting potential for scarless therapies.

This study found that among male university students in South Dakota, hair loss, including thinning and receding hairlines, impacted their psychological well-being, with 32% bothered by their hair condition, highlighting the importance of treatment options and open discussion to improve confidence and reduce distress.

Inherited ichthyosis negatively impacts quality of life, affecting daily activities, self-image, and reproductive decisions.