This study observed that cashmere production and secondary hair follicle activity in Inner Mongolian ewe goats showed age-related differences, with younger goats (aged 2-4 years) having greater production and follicle activity correlating positively with higher antioxidant capacity and lower oxidative stress.
January 2024 in “American journal of clinical dermatology” This study reports that ritlecitinib, when used for up to 24 months in patients aged 12 and older with alopecia areata, has an acceptable safety profile, with a similar proportion of adverse events in both ritlecitinib and placebo groups in the placebo-controlled cohort.
October 2023 in “Journal of the American Academy of Dermatology” This source reports that clascoterone cream has been approved in the U.S. for treating acne vulgaris in patients aged 12 and older, suggesting it works by competing with dihydrotestosterone at androgen receptors to mitigate acne's effects.
October 2023 in “International Journal of Science and Research (IJSR)” This paper describes Grahams Little Piccardi Lassueur Syndrome, a rare type of Lichen Planopilaris that causes different types of alopecia and distinctive skin papules, primarily affecting females aged 40 to 70, and notes the current challenges in treatment options, particularly once scarring occurs.
October 2023 in “International journal of rheumatic diseases” This study found that the JAK3/TEC kinase inhibitor ritlecitinib was effective and well tolerated in patients aged 12 and older with alopecia areata, providing a potential systemic treatment option for this condition, especially in cases of significant psychosocial impact.
June 2023 in “Diyala Journal of Medicine” In this Baquba city study, alopecia areata was more prevalent among males aged 21 to 30, with most experiencing single lesions on the head, recurring cases, and a history of psychological stress.
In this study, significant hair loss was found to be less common among white male CEOs aged 50-69 years than in the general white male population.
Using 5% minoxidil foam twice daily can help regrow hair, especially in younger men aged 20-30.
August 2019 in “Jurnal Biosains Pascasarjana” In this study, acupuncture therapy targeting specific points significantly reduced hair loss in women aged 31-50 with androgenic alopecia.
February 2019 in “Obstetrics and gynaecology cases - reviews” This study compared hirsutism levels, hand measurements, testosterone, and DHEAS levels in women aged 18 to 38 but does not report new definitive findings.
In this study, subcutaneous injection of mesenchymal stem cell-conditioned medium promoted regeneration of mice skin aged by D-galactose, improving skin thickness, vascularization, and collagen density.
This study found that type XVII collagen (COL17) regulates interfollicular epidermis proliferation in both neonatal and aged mice through Wnt signaling, suggesting its potential as a target for anti-aging skin strategies.
This study found that Smad4 is crucial for satellite cell amplification during skeletal muscle regeneration, with aged cells exhibiting less Smad4 and reduced regenerative capability in mice.
This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.
This study found that scalp care using micro-needle therapy was effective in improving hair density and thickness in middle-aged women with menopausal symptoms compared to a control group.
This study found that a combined intake of enzyme food and collagen significantly improved various aspects of hair health in middle-aged women compared to taking either supplement alone or none.
January 2015 in “한국미용학회지” This study found that a combined intake of enzyme food and collagen was more effective than either alone in improving scalp hair characteristics in middle-aged women.
Trichorrhexis nodosa causes hair to break easily, often affecting young to middle-aged black women.
January 2017 in “Indian journal of health sciences and biomedical research KLEU” This study found no association between androgenetic alopecia and increased prostate volume or serum PSA levels in male patients aged 25–45.
This study suggests that the use of finasteride and dutasteride may be linked to a decreased risk of melanoma in white men aged ≥60 years who have benign or malignant prostate tumors.
193 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that the prevalence of androgenetic alopecia increases with age among both men and women in Maryborough, Australia, with 57% of women and 73.5% of men aged 80 and over affected.
124 citations
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July 2017 in “eLife” This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.
110 citations
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November 1984 in “The American Journal of Medicine” This study observed that children with a genetically transmitted defect in the 1,25-dihydroxyvitamin D3 receptor experienced spontaneous healing of rickets as they aged, despite persistent mineral imbalances during treatment.
63 citations
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January 2010 in “Frontiers in Aging Neuroscience” This study found that 3alpha-diol, an androgen metabolite, improved cognitive and affective performance in aged male rats, suggesting its role in countering age-related decline in hippocampally-influenced behaviors.
62 citations
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October 2019 in “Liver International” This study found that polycystic ovary syndrome is independently associated with more severe non-alcoholic steatohepatitis, including advanced fibrosis, in reproductive-aged women with non-alcoholic fatty liver disease.
60 citations
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November 2023 in “Biology” This review explores the role of aging-related changes in skin, discussing how impaired skin barrier function may contribute to systemic inflammation, or "inflamm-aging," which in turn could impact the broader decline in organ and tissue function seen in aged individuals.
48 citations
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May 2015 in “PLOS ONE” This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.
33 citations
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March 2017 in “Dermatologic Surgery” In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.
31 citations
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January 2014 in “Clinical Endocrinology” This study found no significant differences in metabolic characteristics between different phenotypes of PCOS or between women with PCOS and healthy controls among reproductive-aged Iranian women.
25 citations
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May 2020 in “Aesthetic Surgery Journal” In this systematic review, tSVF-based therapy demonstrated favorable outcomes for various pathologies, including aged skin and osteoarthritis, with low incidence of adverse events, while highlighting the need for further research into optimal protocols and mechanisms of action.