Grahams Little Piccardi Lausseur Syndrome: A Rare Case Report with Literature Review

Grahams Little Piccardi Lausseur Syndrome (GLPLS) is a rare form of Lichen planopilaris, mainly affecting women aged 40-70, characterized by scarring alopecia on the scalp, non-scarring alopecia in the axilla and pubic regions, and follicular spinous papules on the trunk and extremities. Diagnosis is through clinical examination and histopathology, with the condition linked to defective cell-mediated immunity. Treatment options aim to halt progression and include retinoids, Tofacitinib, Hydroxychloroquine, corticosteroids, cyclosporine, anti-malarials, and PUVA therapy, but scarring alopecia is irreversible. Early diagnosis is crucial to prevent complications.