24 citations
,
March 2017 in “Journal of The European Academy of Dermatology and Venereology” This study reported a significant increase in the reporting of sexual dysfunction associated with finasteride use, especially in individuals aged 31-45.
23 citations
,
October 2024 in “British Journal of Dermatology” In this study, ritlecitinib showed sustained effectiveness and a favorable safety profile in treating alopecia areata in patients aged 12 and older over 24 months, with improvements observed in hair and eyebrow regrowth and patient satisfaction.
22 citations
,
December 2007 in “Dermatologic Surgery” This study found that dermatology leads in performing office-based cosmetic procedures compared to other specialties, with a focus on white, female patients aged 40 to 59.
21 citations
,
July 2014 in “British Journal of Dermatology” In this study, hair loss in Japanese men with androgenetic alopecia was found to be primarily due to hair follicle miniaturization rather than hair shedding, particularly in those aged 25 and older.
21 citations
,
June 2002 in “PubMed” This study found an association between vertex baldness and prostate cancer, especially for high-grade tumors in men aged 60-69, suggesting a possible shared androgen pathway.
20 citations
,
October 2019 in “JAMA Otolaryngology–Head & Neck Surgery” This study found that the incidence of head and neck melanoma has increased by 51.1% among pediatric, adolescent, and young adult populations in North America over the past 20 years, primarily affecting males aged 15 to 39 years.
14 citations
,
May 2022 in “Frontiers in Endocrinology” This study found that lower serum testosterone levels were significantly associated with an increased prevalence of kidney stones in men over 40, but not in those aged 20–40.
13 citations
,
September 2017 in “Oncotarget” This study suggests that increased Wnt signaling may cause melanocyte stem cell exhaustion, leading to hair graying in aged mice by promoting excessive differentiation of melanocytes.
12 citations
,
June 2015 in “Dermatology Reports” This study found that discoid lupus erythematous was the most common type of primary cicatricial alopecia, predominantly affecting middle-aged women.
11 citations
,
November 2009 in “Brazilian Journal of Medical and Biological Research” This study found that young C57BL/6 and BALB/c mice exhibit distinct regenerative patterns during ear wound healing, with greater wound closure but less regeneration in middle-aged C57BL/6 mice.
10 citations
,
January 2018 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” In this community-based study, the researchers found high prevalence rates of hair loss, baldness, dandruff, and greying among men aged 18-50 in Thiruvallur district, India.
10 citations
,
January 2015 in “The Journal of Clinical Pharmacology” In this study, no statistically significant association was found between finasteride use and the risk of acute pancreatitis in Taiwanese males aged 40-84.
5 citations
,
October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the authors found that inhibiting Cdc42 activity with CASIN restored hair follicle stem cell function and hair growth in aged mice, suggesting potential for treating aging-related hair regeneration issues.
4 citations
,
July 2024 in “BMC Zoology” This study found that the structure and mineral content of dromedary camel hair, specifically the medulla patterns, medulla index, and elemental composition, change with age, revealing differences among camels aged 1 year, 3-5 years, and 8-10 years.
4 citations
,
November 2023 in “SKIN The Journal of Cutaneous Medicine” In this study, ritlecitinib, an oral JAK3/TEC inhibitor, was evaluated for safety in patients aged 12 and older with alopecia areata across four clinical trials up to 36 months, showing a safety profile with reported adverse events and lab abnormalities summarized per dosing groups.
3 citations
,
September 2020 in “Cancer Prevention Research” This study found that health insurance mandates following the Affordable Care Act increased colorectal cancer screening rates by 2.8 percentage points among U.S. adults aged 50 to 74.
3 citations
,
June 2017 in “Methods” This study used computational modeling to identify key genes and miRs involved in cardiac aging, finding a strong relationship supported by literature and some experimental validation in aged mouse hearts.
2 citations
,
December 2025 in “Cosmetics” This review reports on the effects of aging on hair characteristics such as pigmentation, growth, and structural properties across genders and ethnicities, highlighting the importance of scalp health and suggesting cosmetic solutions to improve the appearance of aged hair.
2 citations
,
May 2025 in “Journal of the European Academy of Dermatology and Venereology” In this study, daily treatment with ritlecitinib for up to 24 months led to significant reductions in high-severity alopecia areata SALT scores among patients aged ≥12 years, including those with severe forms such as alopecia totalis and universalis.
2 citations
,
June 2024 in “Journal of the Korean Society of Cosmetology” In this study, 8-week hair loss management combined with aroma scalp massage did not significantly change hair thickness or density but improved scalp moisture and subjective satisfaction among 16 participants aged 20–50.
2 citations
,
September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study reported that AutoML effectively modeled itching and pain development, as well as app use, in patients with chronic eczema or psoriasis using a smartphone monitoring app, revealing that factors like BMI, age, and disease activity significantly influenced app engagement.
2 citations
,
October 2022 in “Journal of structural biology” This study found that age-related hair thinning in Caucasian women over 50 involves significant structural changes within the hair follicle, suggesting an "aged hair program" rather than just producing thinner hairs.
2 citations
,
January 2021 in “JAAD Case Reports” This article reviews potential causes for angiolymphoid hyperplasia with eosinophilia, a benign vascular tumor often found in middle-aged adults, and reports no new clinical findings.
1 citations
,
January 2024 in “Acta Bioclínica” This study examines the significance of understanding conditions like androgenic alopecia, which affects a high percentage of Mexican men (80% of those aged 15–69) and women (50% aged 15–79), and emphasizes the need for better educational resources and therapeutic options in medical training.
1 citations
,
October 2023 in “Journal of Education Health and Sport” In this study, researchers reported that acne is a complex and chronic skin condition most commonly affecting individuals aged 11 to 30, with more severe cases observed more frequently in men and areas rich in sebaceous glands like the face, back, and chest.
1 citations
,
June 2023 in “BMC Pediatrics” In this prospective cohort study conducted in Iraq, 15.2% of children with confirmed COVID-19 experienced persistent symptoms beyond 12 weeks; common symptoms included fatigue and hair fall, with children aged 11-16 at greater risk.
1 citations
,
December 2022 in “Biomolecules & therapeutics” This study found that a long-term astrocyte culture model can effectively study astrocyte senescence and suggests minoxidil as a potential candidate to regulate brain aging by normalizing dysregulated gene expression in aged astrocytes.
1 citations
,
May 2021 in “Research journal of topical and cosmetic sciences” This study observed that taking 500mg/day of Microcore’s Muttaijow ComplexTM for 12 weeks significantly improved the appearance of skin, hair, and nails in healthy middle-aged adults.
1 citations
,
February 2020 in “International Journal of Research in Dermatology” This study describes the clinical profile of scalp alopecia areata among patients at a tertiary care hospital, finding it more common in males, particularly those aged 21-30, with sudden onset and often asymptomatic progression.
July 2026 in “Our Dermatology Online” This study observed a significant rise and fall in black hair dye dermatitis cases over six years, primarily affecting middle-aged men, with most cases presenting as chronic pigmented lichenoid photodermatitis.