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PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

High androgen levels in young women with PCOS are linked to higher blood pressure.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Stress can worsen skin conditions by affecting hormone levels and immune response.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Melatonin may help treat PCOS symptoms in rats.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.