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A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.

SCD1 is crucial for skin health and overall energy balance.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Fat under the skin releases HGF which helps hair grow and gain color.

High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Obesity is linked to various skin conditions and issues, and losing weight can improve these conditions.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

People with Primary Cicatricial Alopecia have a higher risk of heart disease.

PCOS patients have more central body fat, which can be effectively measured using DEXA.

Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.

Curcumin supplements increase adiponectin and decrease leptin in adults.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Using stem cell-enriched fat injections before hair transplant surgery can result in less hair loss and thicker hair.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Fat cells help recruit healing cells and build skin structure during wound healing.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.